Tamiflu and Drug resistance - a phase IV clinical study of FDA data

Summary:

Drug resistance is reported as a side effect among people who take Tamiflu (oseltamivir phosphate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Xtandi, and have H1n1 influenza.

The phase IV clinical study analyzes which people have Drug resistance when taking Tamiflu. It is created by eHealthMe based on reports of 21,270 people who have side effects when taking Tamiflu from the FDA, and is updated regularly.

What is Tamiflu?

Tamiflu has active ingredients of oseltamivir phosphate. It is often used in the flu. eHealthMe is studying from 22,209 Tamiflu users. Check the latest studies of Tamiflu.

What is Drug resistance?

Drug resistance (reduction in effectiveness of a drug) is found to be associated with 828 drugs and 1,057 conditions by eHealthMe. Check the latest studies of Drug resistance.

On Aug, 02, 2026

21,270 people reported to have side effects when taking Tamiflu.
Among them, 42 people (0.2%) have Drug resistance.

Among these 42 people:

How long have people been on Tamiflu when they have Drug resistance? *

What is the gender of people who have Drug resistance when taking Tamiflu? *

female: 44 %
male: 56 %

What is the age of people who have Drug resistance when taking Tamiflu? *

What are other drugs people take besides Tamiflu? *

What are other side effects people have besides Drug resistance? *

Death: 7 people, 16.67%
Drug Ineffective: 5 people, 11.90%
Pneumonia: 4 people, 9.52%
Acute Kidney Failure: 2 people, 4.76%
Septic Shock (shock due to blood infection): 2 people, 4.76%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 4.76%
Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 2 people, 4.76%
Pathogen Resistance: 2 people, 4.76%
Consciousness - Decreased: 1 person, 2.38%
General Physical Health Deterioration (weak health status): 1 person, 2.38%

What are the existing conditions these people have? *

H1n1 Influenza (flu (influenza), which is caused by virus influenza a (h1n1)): 9 people, 21.43%
Avian Influenza (bird flu): 3 people, 7.14%
Sinusitis (inflammation of sinus): 2 people, 4.76%
Cholecystitis (infection of gallbladder): 2 people, 4.76%
Pneumonia: 2 people, 4.76%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 4.76%
Malignant Neoplasm Progression (cancer tumour came back): 2 people, 4.76%
Chronic Lymphocytic Leukaemia Refractory (a cancer of blood cells lymphocytes that no longer responds favourably to treatment): 2 people, 4.76%
Cytomegalovirus Infection: 2 people, 4.76%
Urination - Excessive Volume: 1 person, 2.38%

* Approximation only. Some reports may have incomplete information.

Do you take Tamiflu and have Drug resistance?

- Check whether Drug resistance is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tamiflu:

Tamiflu (22,209 reports)

Drug resistance treatments and more:

Drug resistance (24,513 reports)

Browse all side effects of Tamiflu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug resistance:

Drug resistance (828 drugs)

Browse all the conditions that are associated with Drug resistance:

Drug resistance (1,057 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oseltamivir phosphate (the active ingredients of Tamiflu) and Tamiflu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.