Tapentadol hydrochloride and Hyperhidrosis - a phase IV clinical study of FDA data

Summary:

Hyperhidrosis is reported as a side effect among people who take Tapentadol hydrochloride (tapentadol hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Duloxetine Hydrochloride, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hyperhidrosis when taking Tapentadol hydrochloride. It is created by eHealthMe based on reports of 1,317 people who have side effects when taking Tapentadol hydrochloride from the FDA, and is updated regularly.

What is Tapentadol hydrochloride?

Tapentadol hydrochloride has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 1,343 Tapentadol hydrochloride users. Check the latest studies of Tapentadol hydrochloride.

What is Hyperhidrosis?

Hyperhidrosis (abnormally increased sweating) is found to be associated with 2,553 drugs and 3,546 conditions by eHealthMe. Check the latest studies of Hyperhidrosis.

On Jul, 14, 2026

1,317 people reported to have side effects when taking Tapentadol hydrochloride.
Among them, 25 people (1.9%) have Hyperhidrosis.

Could Tapentadol hydrochloride cause Hyperhidrosis?

Among these 25 people:

How long have people been on Tapentadol hydrochloride when they have Hyperhidrosis? *

What is the gender of people who have Hyperhidrosis when taking Tapentadol hydrochloride? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Hyperhidrosis when taking Tapentadol hydrochloride? *

What are other drugs people take besides Tapentadol hydrochloride? *

Zopiclone: 12 people, 48.00%
Duloxetine Hydrochloride: 12 people, 48.00%
Methylprednisolone: 11 people, 44.00%
Aripiprazole: 11 people, 44.00%
Atenolol: 11 people, 44.00%
Cetirizine Hydrochloride: 11 people, 44.00%
Claritin: 11 people, 44.00%
Clonazepam: 11 people, 44.00%
Cymbalta: 11 people, 44.00%
Dilaudid: 11 people, 44.00%

What are other side effects people have besides Hyperhidrosis? *

Drug Ineffective: 16 people, 64.00%
Dizziness: 16 people, 64.00%
Fatigue (feeling of tiredness): 14 people, 56.00%
Fainting (loss of consciousness and postural tone): 14 people, 56.00%
Dyspnea (difficult or laboured breathing): 14 people, 56.00%
Diarrhea: 13 people, 52.00%
Nausea (feeling of having an urge to vomit): 13 people, 52.00%
Abdominal Pain Upper: 13 people, 52.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 13 people, 52.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 48.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 52.00%
Hypersensitivity: 10 people, 40.00%
Sleep Disorder: 8 people, 32.00%
Depression: 4 people, 16.00%
Back Pain: 2 people, 8.00%
Thyroid Diseases: 1 person, 4.00%
Procedural Pain: 1 person, 4.00%
Neuralgia (pain in one or more nerves): 1 person, 4.00%
Neck Pain: 1 person, 4.00%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tapentadol hydrochloride and have Hyperhidrosis?

- Check whether Hyperhidrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tapentadol hydrochloride:

Tapentadol hydrochloride (1,343 reports)

Hyperhidrosis treatments and more:

Hyperhidrosis (147,206 reports)

Browse all side effects of Tapentadol hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperhidrosis:

Hyperhidrosis (2,553 drugs)

Browse all the conditions that are associated with Hyperhidrosis:

Hyperhidrosis (3,546 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tapentadol hydrochloride (the active ingredients of Tapentadol hydrochloride) and Tapentadol hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.