Tapentadol and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Tapentadol (tapentadol), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Prednisolone, and have Pain.

The phase IV clinical study analyzes which people have Joint pain when taking Tapentadol. It is created by eHealthMe based on reports of 2,486 people who have side effects when taking Tapentadol from the FDA, and is updated regularly.

What is Tapentadol?

Tapentadol has active ingredients of tapentadol. It is often used in chronic pain. eHealthMe is studying from 2,551 Tapentadol users. Check the latest studies of Tapentadol.

What is Joint pain?

Joint pain is found to be associated with 3,329 drugs and 5,209 conditions by eHealthMe. Check the latest studies of Joint pain.

On Jul, 27, 2026

2,486 people reported to have side effects when taking Tapentadol.
Among them, 70 people (2.82%) have Joint pain.

Among these 70 people:

How long have people been on Tapentadol when they have Joint pain? *

What is the gender of people who have Joint pain when taking Tapentadol? *

female: 76.36 %
male: 23.64 %

What is the age of people who have Joint pain when taking Tapentadol? *

What are other drugs people take besides Tapentadol? *

What are other side effects people have besides Joint pain? *

Pain: 31 people, 44.29%
Osteoporosis (bones weak and more likely to break): 22 people, 31.43%
Hair Loss: 21 people, 30.00%
Leukopenia (less number of white blood cells in blood): 20 people, 28.57%
Stress And Anxiety: 20 people, 28.57%
Asthma: 18 people, 25.71%
Tinnitus (a ringing in the ears): 17 people, 24.29%
Dry Mouth: 17 people, 24.29%
Back Pain: 16 people, 22.86%
Joint Stiffness: 16 people, 22.86%

What are the existing conditions these people have? *

Pain: 16 people, 22.86%
Hiv Infection: 15 people, 21.43%
High Blood Pressure: 10 people, 14.29%
Back Pain: 9 people, 12.86%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 10.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 8.57%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 8.57%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 4 people, 5.71%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 5.71%
Malignant Melanoma (skin cancer rises from melancytes): 3 people, 4.29%

* Approximation only. Some reports may have incomplete information.

Do you take Tapentadol and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tapentadol:

Tapentadol (2,551 reports)

Joint pain treatments and more:

Joint pain (542,934 reports)

Browse all side effects of Tapentadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,329 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tapentadol (the active ingredients of Tapentadol) and Tapentadol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.