Tecfidera and Cd4 lymphocytes decreased - a phase IV clinical study of FDA data

Summary:

Cd4 lymphocytes decreased is reported as a side effect among people who take Tecfidera (dimethyl fumarate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Tysabri, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Cd4 lymphocytes decreased when taking Tecfidera. It is created by eHealthMe based on reports of 129,391 people who have side effects when taking Tecfidera from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Cd4 lymphocytes decreased?

Cd4 lymphocytes decreased is found to be associated with 249 drugs and 343 conditions by eHealthMe. Check the latest studies of Cd4 lymphocytes decreased.

On Aug, 06, 2026

129,391 people reported to have side effects when taking Tecfidera.
Among them, 70 people (0.05%) have Cd4 lymphocytes decreased.

Could Tecfidera cause Cd4 lymphocytes decreased?

Among these 70 people:

How long have people been on Tecfidera when they have Cd4 lymphocytes decreased? *

What is the gender of people who have Cd4 lymphocytes decreased when taking Tecfidera? *

female: 60.29 %
male: 39.71 %

What is the age of people who have Cd4 lymphocytes decreased when taking Tecfidera? *

What are other drugs people take besides Tecfidera? *

What are other side effects people have besides Cd4 lymphocytes decreased? *

Cd8 Lymphocytes Decreased: 30 people, 42.86%
Lymphocyte Count Decreased: 23 people, 32.86%
White Blood Cell Count Decreased: 22 people, 31.43%
T-Lymphocyte Count Decreased: 17 people, 24.29%
Lymphopenia (an abnormally low level of lymphocytes in the blood): 12 people, 17.14%
Fatigue (feeling of tiredness): 12 people, 17.14%
Nasopharyngitis (inflammation of the nasopharynx): 9 people, 12.86%
Speech Impairment (Adult) (inability to speak (adult)): 8 people, 11.43%
Fever: 7 people, 10.00%
Herpes Zoster: 7 people, 10.00%

What are the existing conditions these people have? *

Hypersensitivity: 9 people, 12.86%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 8.57%
Stress And Anxiety: 6 people, 8.57%
Depression: 6 people, 8.57%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 6 people, 8.57%
Muscle Spasms (muscle contraction): 6 people, 8.57%
Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis): 4 people, 5.71%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 4.29%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 4.29%
Asthma: 3 people, 4.29%

* Approximation only. Some reports may have incomplete information.

Do you take Tecfidera and have Cd4 lymphocytes decreased?

- Check whether Cd4 lymphocytes decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tecfidera:

Tecfidera (129,627 reports)

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cd4 lymphocytes decreased:

Cd4 lymphocytes decreased (249 drugs)

Browse all the conditions that are associated with Cd4 lymphocytes decreased:

Cd4 lymphocytes decreased (343 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate (the active ingredients of Tecfidera) and Tecfidera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.