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Tecfidera and Salivary hypersecretion - a phase IV clinical study of FDA data

Summary:

Salivary hypersecretion is reported as a side effect among people who take Tecfidera (dimethyl fumarate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Ampyra, and have Constipation.

The phase IV clinical study analyzes which people have Salivary hypersecretion when taking Tecfidera. It is created by eHealthMe based on reports of 129,391 people who have side effects when taking Tecfidera from the FDA, and is updated regularly.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

What is Salivary hypersecretion?

Salivary hypersecretion (excess saliva secretion) is found to be associated with 784 drugs and 1,337 conditions by eHealthMe. Check the latest studies of Salivary hypersecretion.

On Aug, 01, 2026

129,391 people reported to have side effects when taking Tecfidera.
Among them, 47 people (0.04%) have Salivary hypersecretion.

Could Tecfidera cause Salivary hypersecretion?

Among these 47 people:

How long have people been on Tecfidera when they have Salivary hypersecretion? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Salivary hypersecretion when taking Tecfidera? *

  • female: 74.47 %
  • male: 25.53 %

What is the age of people who have Salivary hypersecretion when taking Tecfidera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10.0 %
  • 30-39: 22.5 %
  • 40-49: 35.0 %
  • 50-59: 25.0 %
  • 60+: 7.5 %

What are other drugs people take besides Tecfidera? *

  1. Ampyra: 5 people, 10.64%
  2. Aricept: 4 people, 8.51%
  3. Enablex: 3 people, 6.38%
  4. Nexium: 3 people, 6.38%
  5. Wellbutrin: 3 people, 6.38%
  6. Vitamin D: 3 people, 6.38%
  7. Vitamin C: 3 people, 6.38%
  8. B12: 2 people, 4.26%
  9. Amlodipine Besylate: 2 people, 4.26%
  10. Avonex: 2 people, 4.26%

What are other side effects people have besides Salivary hypersecretion? *

  1. Nausea (feeling of having an urge to vomit): 22 people, 46.81%
  2. Skin Blushing/flushing (a sudden reddening of the face, neck): 10 people, 21.28%
  3. Nausea And Vomiting: 10 people, 21.28%
  4. Abdominal Discomfort: 9 people, 19.15%
  5. Abdominal Pain Upper: 9 people, 19.15%
  6. Memory Loss: 6 people, 12.77%
  7. Diarrhea: 6 people, 12.77%
  8. Indigestion: 6 people, 12.77%
  9. Fatigue (feeling of tiredness): 6 people, 12.77%
  10. Feeling Hot: 6 people, 12.77%

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 1 person, 2.13%
  2. Mood Swings (an extreme or rapid change in mood): 1 person, 2.13%
  3. Hyperhidrosis (abnormally increased sweating): 1 person, 2.13%
  4. Headache (pain in head): 1 person, 2.13%
  5. Gait Disturbance: 1 person, 2.13%
  6. Fatigue (feeling of tiredness): 1 person, 2.13%
  7. Constipation: 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Tecfidera and have Salivary hypersecretion?

- Check whether Salivary hypersecretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tecfidera:

Salivary hypersecretion treatments and more:

How severe was Salivary hypersecretion and when was it recovered:

Expand to all the drugs that have ingredients of dimethyl fumarate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tecfidera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Salivary hypersecretion:

Browse all the conditions that are associated with Salivary hypersecretion:

How the study uses the data?

The study uses data from the FDA. It is based on dimethyl fumarate (the active ingredients of Tecfidera) and Tecfidera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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