Tegretol and Anaphylactoid reaction - a phase IV clinical study of FDA data

Summary:

Anaphylactoid reaction is reported as a side effect among people who take Tegretol (carbamazepine), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Fabrazyme, and have Fabry's disease.

The phase IV clinical study analyzes which people have Anaphylactoid reaction when taking Tegretol. It is created by eHealthMe based on reports of 44,100 people who have side effects when taking Tegretol from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Anaphylactoid reaction?

Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation) is found to be associated with 410 drugs and 724 conditions by eHealthMe. Check the latest studies of Anaphylactoid reaction.

On Aug, 10, 2026

44,100 people reported to have side effects when taking Tegretol.
Among them, 22 people (0.05%) have Anaphylactoid reaction.

Could Tegretol cause Anaphylactoid reaction?

Among these 22 people:

How long have people been on Tegretol when they have Anaphylactoid reaction? *

What is the gender of people who have Anaphylactoid reaction when taking Tegretol? *

female: 19.05 %
male: 80.95 %

What is the age of people who have Anaphylactoid reaction when taking Tegretol? *

What are other drugs people take besides Tegretol? *

What are other side effects people have besides Anaphylactoid reaction? *

Infusion Related Reaction: 11 people, 50.00%
Rashes (redness): 11 people, 50.00%
Oxygen Saturation Decreased: 11 people, 50.00%
Cough: 11 people, 50.00%
Tremor (trembling or shaking movements in one or more parts of your body): 10 people, 45.45%
Bradycardia (abnormally slow heart action): 10 people, 45.45%
Chills (felling of cold): 9 people, 40.91%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 7 people, 31.82%
Hyperhidrosis (abnormally increased sweating): 3 people, 13.64%
Feeling Cold: 3 people, 13.64%

What are the existing conditions these people have? *

Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 11 people, 50.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 9.09%
Swallowing Difficulty: 1 person, 4.55%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 4.55%
Pain: 1 person, 4.55%
Oedema (fluid collection in tissue): 1 person, 4.55%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1 person, 4.55%
Herpes Zoster: 1 person, 4.55%
Facial Spasm (involuntary muscle contractions face): 1 person, 4.55%
Diabetes: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Tegretol and have Anaphylactoid reaction?

- Check whether Anaphylactoid reaction is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegretol:

Tegretol (45,969 reports)

Browse all side effects of Tegretol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylactoid reaction:

Anaphylactoid reaction (410 drugs)

Browse all the conditions that are associated with Anaphylactoid reaction:

Anaphylactoid reaction (724 conditions)

Related publications that referenced our studies

Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine (the active ingredients of Tegretol) and Tegretol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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