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Tegretol and Fluid retention - a phase IV clinical study of FDA data

Summary:

Fluid retention is reported as a side effect among people who take Tegretol (carbamazepine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Nexium, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Fluid retention when taking Tegretol. It is created by eHealthMe based on reports of 44,100 people who have side effects when taking Tegretol from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Fluid retention?

Fluid retention (an abnormal accumulation of fluid in the blood) is found to be associated with 1,700 drugs and 2,448 conditions by eHealthMe. Check the latest studies of Fluid retention.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 26, 2026

44,100 people reported to have side effects when taking Tegretol.
Among them, 68 people (0.15%) have Fluid retention.

Could Tegretol cause Fluid retention?

Among these 68 people:

How long have people been on Tegretol when they have Fluid retention? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fluid retention when taking Tegretol? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Fluid retention when taking Tegretol? *

  • 0-1: 4 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2 %
  • 30-39: 14 %
  • 40-49: 12 %
  • 50-59: 24 %
  • 60+: 44 %

What are other drugs people take besides Tegretol? *

  1. Nexium: 10 people, 14.71%
  2. Avonex: 8 people, 11.76%
  3. Coumadin: 8 people, 11.76%
  4. Neurontin: 7 people, 10.29%
  5. Premarin: 7 people, 10.29%
  6. Lyrica: 6 people, 8.82%
  7. Levothyroxine Sodium: 5 people, 7.35%
  8. Aspirin: 5 people, 7.35%
  9. Lasix: 4 people, 5.88%
  10. Keppra: 4 people, 5.88%

What are other side effects people have besides Fluid retention? *

  1. Weight Increased: 16 people, 23.53%
  2. Hypotension (abnormally low blood pressure): 10 people, 14.71%
  3. Malaise (a feeling of general discomfort or uneasiness): 7 people, 10.29%
  4. Dyspnea (difficult or laboured breathing): 7 people, 10.29%
  5. Peripheral Swelling: 6 people, 8.82%
  6. Abasia (inability to walk): 5 people, 7.35%
  7. Speech Impairment (Adult) (inability to speak (adult)): 5 people, 7.35%
  8. Insomnia (sleeplessness): 5 people, 7.35%
  9. Heart Rate Increased: 5 people, 7.35%
  10. Fever: 5 people, 7.35%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.24%
  2. Depression: 8 people, 11.76%
  3. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 4 people, 5.88%
  4. Pain: 4 people, 5.88%
  5. Sleep Disorder: 3 people, 4.41%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 4.41%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 4.41%
  8. High Blood Cholesterol: 2 people, 2.94%
  9. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 2 people, 2.94%
  10. Diabetes: 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Tegretol and have Fluid retention?

- Check whether Fluid retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegretol:

Fluid retention treatments and more:

How severe was Fluid retention and when was it recovered:

Expand to all the drugs that have ingredients of carbamazepine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tegretol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid retention:

Browse all the conditions that are associated with Fluid retention:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine (the active ingredients of Tegretol) and Tegretol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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