Tegretol and Systolic dysfunction - a phase IV clinical study of FDA data

Summary:

Systolic dysfunction is reported as a side effect among people who take Tegretol (carbamazepine), especially for people who are female, 10-19 old, also take Uptravi, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Systolic dysfunction when taking Tegretol. It is created by eHealthMe based on reports of 44,100 people who have side effects when taking Tegretol from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Systolic dysfunction?

Systolic dysfunction (impaired ventricular contraction) is found to be associated with 198 drugs and 220 conditions by eHealthMe. Check the latest studies of Systolic dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

44,100 people reported to have side effects when taking Tegretol.
Among them, 16 people (0.04%) have Systolic dysfunction.

Could Tegretol cause Systolic dysfunction?

Among these 16 people:

What is the gender of people who have Systolic dysfunction when taking Tegretol? *

female: 100 %
male: 0.0 %

What is the age of people who have Systolic dysfunction when taking Tegretol? *

What are other drugs people take besides Tegretol? *

What are other side effects people have besides Systolic dysfunction? *

Rhinorrhea (watery mucus discharge from the nose): 16 people, 100.00%
Loss Of Consciousness: 16 people, 100.00%
Dizziness: 16 people, 100.00%
Fainting (loss of consciousness and postural tone): 16 people, 100.00%
Fatigue (feeling of tiredness): 16 people, 100.00%
Fever: 16 people, 100.00%
High Blood Pressure: 16 people, 100.00%
Kidney Infection: 16 people, 100.00%
Metapneumovirus Infection (infection with human metapneumovirus): 16 people, 100.00%
Pulse Abnormal: 16 people, 100.00%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 16 people, 100.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Tegretol and have Systolic dysfunction?

- Check whether Systolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegretol:

Tegretol (45,969 reports)

Browse all side effects of Tegretol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systolic dysfunction:

Systolic dysfunction (198 drugs)

Browse all the conditions that are associated with Systolic dysfunction:

Systolic dysfunction (220 conditions)

Related publications that referenced our studies

Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine (the active ingredients of Tegretol) and Tegretol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.