Tekturna and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Tekturna (aliskiren hemifumarate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Synthroid, and have Malignant hypertension.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Tekturna. It is created by eHealthMe based on reports of 4,498 people who have side effects when taking Tekturna from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,614 drugs and 2,599 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

On Jul, 11, 2026

4,498 people reported to have side effects when taking Tekturna.
Among them, 25 people (0.56%) have Hypothyroidism.

Among these 25 people:

How long have people been on Tekturna when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Tekturna? *

female: 68 %
male: 32 %

What is the age of people who have Hypothyroidism when taking Tekturna? *

What are other drugs people take besides Tekturna? *

What are other side effects people have besides Hypothyroidism? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 44.00%
Acute Kidney Failure: 10 people, 40.00%
Fatigue (feeling of tiredness): 8 people, 32.00%
Sleep Apnea Syndrome: 8 people, 32.00%
Dyspnea (difficult or laboured breathing): 8 people, 32.00%
Diabetes: 8 people, 32.00%
Pain: 8 people, 32.00%
Chronic Kidney Disease: 8 people, 32.00%
Pneumonia: 8 people, 32.00%
Osteoporosis (bones weak and more likely to break): 8 people, 32.00%

What are the existing conditions these people have? *

Malignant Hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage): 3 people, 12.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 8.00%
Weight Loss: 1 person, 4.00%
Type 2 Diabetes: 1 person, 4.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 4.00%
Psychotic Behavior: 1 person, 4.00%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 4.00%
Infertility Male: 1 person, 4.00%
Impaired Gastric Emptying: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tekturna:

Tekturna (4,730 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,065 reports)

Browse all side effects of Tekturna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,614 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,599 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on aliskiren hemifumarate (the active ingredients of Tekturna) and Tekturna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.