Tekturna and Orthostatic hypotension - a phase IV clinical study of FDA data

Summary:

Orthostatic hypotension is reported as a side effect among people who take Tekturna (aliskiren hemifumarate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Diovan, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Orthostatic hypotension when taking Tekturna. It is created by eHealthMe based on reports of 4,498 people who have side effects when taking Tekturna from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Orthostatic hypotension?

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up) is found to be associated with 1,228 drugs and 1,336 conditions by eHealthMe. Check the latest studies of Orthostatic hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

4,498 people reported to have side effects when taking Tekturna.
Among them, 12 people (0.27%) have Orthostatic hypotension.

Could Tekturna cause Orthostatic hypotension?

Among these 12 people:

How long have people been on Tekturna when they have Orthostatic hypotension? *

What is the gender of people who have Orthostatic hypotension when taking Tekturna? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Orthostatic hypotension when taking Tekturna? *

What are other drugs people take besides Tekturna? *

What are other side effects people have besides Orthostatic hypotension? *

Hypotension (abnormally low blood pressure): 8 people, 66.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 58.33%
Heart Rate Decreased: 5 people, 41.67%
Dizziness: 5 people, 41.67%
Stress And Anxiety: 5 people, 41.67%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 33.33%
Fatigue (feeling of tiredness): 4 people, 33.33%
Indigestion: 4 people, 33.33%
Joint Pain: 4 people, 33.33%
Diarrhea: 4 people, 33.33%

What are the existing conditions these people have? *

Type 2 Diabetes: 3 people, 25.00%
Venous Stasis (a condition of slow blood flow in the veins): 2 people, 16.67%
Weight Loss: 1 person, 8.33%
Stress And Anxiety: 1 person, 8.33%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 8.33%
Pain: 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Muscle Spasms (muscle contraction): 1 person, 8.33%
Malignant Hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage): 1 person, 8.33%
Itching: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and have Orthostatic hypotension?

- Check whether Orthostatic hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tekturna:

Tekturna (4,730 reports)

Browse all side effects of Tekturna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,228 drugs)

Browse all the conditions that are associated with Orthostatic hypotension:

Orthostatic hypotension (1,336 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aliskiren hemifumarate (the active ingredients of Tekturna) and Tekturna (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.