Temodar and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Temodar (temozolomide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Glioblastoma.

The phase IV clinical study analyzes which people have Constipation when taking Temodar. It is created by eHealthMe based on reports of 6,563 people who have side effects when taking Temodar from the FDA, and is updated regularly.

What is Temodar?

Temodar has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 6,683 Temodar users. Check the latest studies of Temodar.

What is Constipation?

Constipation is found to be associated with 3,003 drugs and 4,563 conditions by eHealthMe. Check the latest studies of Constipation.



On Jul, 31, 2025

6,563 people reported to have side effects when taking Temodar.
Among them, 172 people (2.62%) have Constipation.

Could Temodar cause Constipation?

Among these 172 people:

How long have people been on Temodar when they have Constipation? *

  • < 1 month: 43.9 %
  • 1 - 6 months: 31.71 %
  • 6 - 12 months: 14.63 %
  • 1 - 2 years: 7.32 %
  • 2 - 5 years: 2.44 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Constipation when taking Temodar? *

  • female: 34.36 %
  • male: 65.64 %

What is the age of people who have Constipation when taking Temodar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.22 %
  • 30-39: 8.89 %
  • 40-49: 25.93 %
  • 50-59: 24.44 %
  • 60+: 38.52 %

What are other drugs people take besides Temodar? *

  1. Zofran: 39 people, 22.67%
  2. Decadron: 23 people, 13.37%
  3. Avastin: 21 people, 12.21%
  4. Keppra: 16 people, 9.30%
  5. Zoloft: 13 people, 7.56%
  6. Thalomid: 13 people, 7.56%
  7. Tylenol: 12 people, 6.98%
  8. Dilantin: 12 people, 6.98%
  9. Dexamethasone: 12 people, 6.98%
  10. Ativan: 11 people, 6.40%

What are other side effects people have besides Constipation? *

  1. Fatigue (feeling of tiredness): 72 people, 41.86%
  2. Nausea (feeling of having an urge to vomit): 58 people, 33.72%
  3. Diarrhea: 35 people, 20.35%
  4. Weakness: 30 people, 17.44%
  5. Nausea And Vomiting: 27 people, 15.70%
  6. Headache (pain in head): 25 people, 14.53%
  7. Thrombocytopenia (decrease of platelets in blood): 24 people, 13.95%
  8. Rashes (redness): 17 people, 9.88%
  9. Pain: 16 people, 9.30%
  10. Confusional State: 15 people, 8.72%

What are the existing conditions these people have? *

  1. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 20 people, 11.63%
  2. Brain Neoplasm Malignant (brain cancer tumour): 15 people, 8.72%
  3. Brain Neoplasm (tumour of brain): 12 people, 6.98%
  4. Malignant Melanoma (skin cancer rises from melancytes): 9 people, 5.23%
  5. Oligodendroglioma (a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell): 8 people, 4.65%
  6. Nausea (feeling of having an urge to vomit): 7 people, 4.07%
  7. High Blood Pressure: 6 people, 3.49%
  8. Pain: 6 people, 3.49%
  9. Malignant Oligodendroglioma (brain cancer tumour): 6 people, 3.49%
  10. Desmoplastic Small Round Cell Tumor: 6 people, 3.49%

* Approximation only. Some reports may have incomplete information.

Do you take Temodar and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Temodar:

Constipation treatments and more:

How severe was Constipation and when was it recovered:

Expand to all the drugs that have ingredients of temozolomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Temodar side effects:

Browse all side effects of Temodar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Constipation:

Browse all the drugs that are associated with Constipation:

Common conditions associated with Constipation:

Browse all the conditions that are associated with Constipation:


How the study uses the data?

The study uses data from the FDA. It is based on temozolomide (the active ingredients of Temodar) and Temodar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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