Temodar and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Temodar (temozolomide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zofran, and have Brain neoplasm malignant.

The phase IV clinical study analyzes which people have Oedema when taking Temodar. It is created by eHealthMe based on reports of 6,563 people who have side effects when taking Temodar from the FDA, and is updated regularly.

What is Temodar?

Temodar has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 6,683 Temodar users. Check the latest studies of Temodar.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,185 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.



On Jul, 20, 2026

6,563 people reported to have side effects when taking Temodar.
Among them, 49 people (0.75%) have Oedema.

Could Temodar cause Oedema?

Among these 49 people:

How long have people been on Temodar when they have Oedema? *

  • < 1 month: 58.82 %
  • 1 - 6 months: 29.41 %
  • 6 - 12 months: 11.76 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Oedema when taking Temodar? *

  • female: 45.83 %
  • male: 54.17 %

What is the age of people who have Oedema when taking Temodar? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.94 %
  • 30-39: 8.82 %
  • 40-49: 20.59 %
  • 50-59: 26.47 %
  • 60+: 41.18 %

What are other drugs people take besides Temodar? *

  1. Zofran: 14 people, 28.57%
  2. Decadron: 13 people, 26.53%
  3. Avastin: 8 people, 16.33%
  4. Thalomid: 8 people, 16.33%
  5. Keppra: 7 people, 14.29%
  6. Tegretol: 6 people, 12.24%
  7. Dilaudid: 5 people, 10.20%
  8. Bactrim Ds: 5 people, 10.20%
  9. Nexium: 5 people, 10.20%
  10. Dilantin: 5 people, 10.20%

What are other side effects people have besides Oedema? *

  1. Weakness: 11 people, 22.45%
  2. Nausea (feeling of having an urge to vomit): 10 people, 20.41%
  3. Fatigue (feeling of tiredness): 10 people, 20.41%
  4. Thrombocytopenia (decrease of platelets in blood): 8 people, 16.33%
  5. Diarrhea: 8 people, 16.33%
  6. Death: 8 people, 16.33%
  7. Acute Kidney Failure: 8 people, 16.33%
  8. Anaemia (lack of blood): 7 people, 14.29%
  9. Hemiparesis (weakness on one side of the body): 7 people, 14.29%
  10. Headache (pain in head): 7 people, 14.29%

What are the existing conditions these people have? *

  1. Brain Neoplasm Malignant (brain cancer tumour): 8 people, 16.33%
  2. Malignant Melanoma (skin cancer rises from melancytes): 5 people, 10.20%
  3. Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 8.16%
  4. Brain Neoplasm (tumour of brain): 3 people, 6.12%
  5. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 6.12%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 4.08%
  7. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 2 people, 4.08%
  8. Headache (pain in head): 2 people, 4.08%
  9. High Blood Pressure: 1 person, 2.04%
  10. Constipation: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Temodar and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Temodar:

Oedema treatments and more:

How severe was Oedema and when was it recovered:

Expand to all the drugs that have ingredients of temozolomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Temodar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Browse all the conditions that are associated with Oedema:


How the study uses the data?

The study uses data from the FDA. It is based on temozolomide (the active ingredients of Temodar) and Temodar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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