Tepezza and Hyperthyroid - a phase IV clinical study of FDA data

Summary:

Hyperthyroid is reported as a side effect among people who take Tepezza (teprotumumab-trbw), especially for people who are female, also take Aspirin, and have Endocrine ophthalmopathy.

The phase IV clinical study analyzes which people have Hyperthyroid when taking Tepezza. It is created by eHealthMe based on reports of 3,630 people who have side effects when taking Tepezza from the FDA, and is updated regularly.

What is Tepezza?

Tepezza has active ingredients of teprotumumab-trbw. eHealthMe is studying from 3,632 Tepezza users. Check the latest studies of Tepezza.

What is Hyperthyroid?

Hyperthyroid is found to be associated with 1,117 drugs and 1,420 conditions by eHealthMe. Check the latest studies of Hyperthyroid.

On Jun, 25, 2026

3,630 people reported to have side effects when taking Tepezza.
Among them, 13 people (0.36%) have Hyperthyroid.

Among these 13 people:

What is the gender of people who have Hyperthyroid when taking Tepezza? *

female: 100 %
male: 0.0 %

What are other drugs people take besides Tepezza? *

What are other side effects people have besides Hyperthyroid? *

Visual Impairment: 6 people, 46.15%
Muscle Spasms (muscle contraction): 6 people, 46.15%
Fatigue (feeling of tiredness): 5 people, 38.46%
Eye Irritation: 5 people, 38.46%
Eye Pain: 5 people, 38.46%
Diarrhea: 5 people, 38.46%
Ocular Hyperaemia (an abnormally large amount of blood in eye): 4 people, 30.77%
Nausea (feeling of having an urge to vomit): 4 people, 30.77%
Blood Pressure Systolic Increased: 3 people, 23.08%
Bradycardia (abnormally slow heart action): 3 people, 23.08%

What are the existing conditions these people have? *

Endocrine Ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism): 8 people, 61.54%
Eye Inflammation: 3 people, 23.08%
Ocular Hyperaemia (an abnormally large amount of blood in eye): 2 people, 15.38%
Hyperglycemia (high blood sugar): 2 people, 15.38%
Eyes - Bulging (swelling of eyes): 2 people, 15.38%
Eyelid Oedema (eyelids are swollen and contain excessive fluid): 2 people, 15.38%
Eye Pain: 2 people, 15.38%
Dry Eyes (lack of adequate tears): 2 people, 15.38%
Blepharitis (chronic inflammation of the eyelid): 2 people, 15.38%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Tepezza and have Hyperthyroid?

- Check whether Hyperthyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tepezza:

Tepezza (3,632 reports)

Hyperthyroid treatments and more:

Hyperthyroid (26,832 reports)

Browse all side effects of Tepezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroid:

Hyperthyroid (1,117 drugs)

Browse all the conditions that are associated with Hyperthyroid:

Hyperthyroid (1,420 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on teprotumumab-trbw (the active ingredients of Tepezza) and Tepezza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.