Tessalon and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Tessalon (benzonatate), especially for people who are female, 60+ old, also take Fosamax, and have Migraine.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Tessalon. It is created by eHealthMe based on reports of 6,327 people who have side effects when taking Tessalon from the FDA, and is updated regularly.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,088 drugs and 1,358 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

On Jul, 11, 2026

6,327 people reported to have side effects when taking Tessalon.
Among them, 12 people (0.19%) have Multiple sclerosis.

Could Tessalon cause Multiple sclerosis?

Among these 12 people:

What is the gender of people who have Multiple sclerosis when taking Tessalon? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Multiple sclerosis when taking Tessalon? *

What are other drugs people take besides Tessalon? *

What are other side effects people have besides Multiple sclerosis? *

Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
Joint Injury: 3 people, 25.00%
Depression: 3 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
Head Injury: 3 people, 25.00%
Herpes Zoster: 3 people, 25.00%
Fall: 3 people, 25.00%
Gastric Cancer Recurrent (repeat stomach cancer): 3 people, 25.00%
Gastric Ulcer (stomach ulcer): 3 people, 25.00%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 3 people, 25.00%

What are the existing conditions these people have? *

Migraine (headache): 4 people, 33.33%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 2 people, 16.67%
The Flu (the flu is caused by an influenza virus): 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Dizziness: 1 person, 8.33%
Dyspnea (difficult or laboured breathing): 1 person, 8.33%
Fatigue (feeling of tiredness): 1 person, 8.33%
Headache (pain in head): 1 person, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%
Neuralgia (pain in one or more nerves): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Tessalon and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tessalon:

Tessalon (6,493 reports)

Browse all side effects of Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Multiple sclerosis (1,088 drugs)

Browse all the conditions that are associated with Multiple sclerosis:

Multiple sclerosis (1,358 conditions)

Related publications that referenced our studies

Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on benzonatate (the active ingredients of Tessalon) and Tessalon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.