Testosterone and Acne - a phase IV clinical study of FDA data

Summary:

Acne is reported as a side effect among people who take Testosterone (testosterone), especially for people who are male, 50-59 old, have been taking the drug for 6 - 12 months also take Tretinoin, and have Drowsiness.

The phase IV clinical study analyzes which people have Acne when taking Testosterone. It is created by eHealthMe based on reports of 5,651 people who have side effects when taking Testosterone from the FDA, and is updated regularly.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

What is Acne?

Acne (skin problems that cause pimples) is found to be associated with 1,313 drugs and 2,340 conditions by eHealthMe. Check the latest studies of Acne.



On Apr, 08, 2026

5,651 people reported to have side effects when taking Testosterone.
Among them, 25 people (0.44%) have Acne.

Could Testosterone cause Acne?

Among these 25 people:

How long have people been on Testosterone when they have Acne? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Acne when taking Testosterone? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Acne when taking Testosterone? *

  • 0-1: 0.0 %
  • 2-9: 8.33 %
  • 10-19: 16.67 %
  • 20-29: 0.0 %
  • 30-39: 25.0 %
  • 40-49: 8.33 %
  • 50-59: 25.0 %
  • 60+: 16.67 %

What are other drugs people take besides Testosterone? *

  1. Magnesium Citrate: 3 people, 12.00%
  2. Pantoprazole Sodium: 3 people, 12.00%
  3. Xywav: 3 people, 12.00%
  4. Buspirone Hcl: 3 people, 12.00%
  5. Tretinoin: 3 people, 12.00%
  6. Dupixent: 2 people, 8.00%
  7. Nandrolone Decanoate: 2 people, 8.00%
  8. Prednisone: 2 people, 8.00%
  9. Metformin: 2 people, 8.00%
  10. Androgel: 2 people, 8.00%

What are other side effects people have besides Acne? *

  1. Muscle Spasms (muscle contraction): 5 people, 20.00%
  2. Limb Injury: 4 people, 16.00%
  3. High Blood Pressure: 4 people, 16.00%
  4. Nausea (feeling of having an urge to vomit): 3 people, 12.00%
  5. Acne Fulminans (acne with highly destructive inflammation-skin disease): 3 people, 12.00%
  6. Kidney Stones: 3 people, 12.00%
  7. Back Injury: 3 people, 12.00%
  8. Fatigue (feeling of tiredness): 3 people, 12.00%
  9. Hepatitis Cholestatic (flow of bile from the liver is slowed or blocked): 2 people, 8.00%
  10. Diarrhea: 2 people, 8.00%

What are the existing conditions these people have? *

  1. Drowsiness: 3 people, 12.00%
  2. Blood Testosterone Decreased: 2 people, 8.00%
  3. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 8.00%
  4. Vitamin D Decreased: 1 person, 4.00%
  5. Virilism (development or possession of male secondary sex characters in a female or prepubertal male): 1 person, 4.00%
  6. Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 1 person, 4.00%
  7. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 4.00%
  8. Blood Testosterone Abnormal: 1 person, 4.00%
  9. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 4.00%
  10. Fatigue (feeling of tiredness): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Testosterone and have Acne?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Testosterone:

Acne treatments and more:

  • Acne (179,010 reports)

How severe was Acne and when was it recovered:

Expand to all the drugs that have ingredients of testosterone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acne:

  • Acne (1,313 drugs)

Browse all the conditions that are associated with Acne:

  • Acne (2,340 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on testosterone (the active ingredients of Testosterone) and Testosterone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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