Thalomid and Melaena - a phase IV clinical study of FDA data

Summary:

Melaena is reported as a side effect among people who take Thalomid (thalidomide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Celebrex, and have Arteriovenous malformation.

The phase IV clinical study analyzes which people have Melaena when taking Thalomid. It is created by eHealthMe based on reports of 38,055 people who have side effects when taking Thalomid from the FDA, and is updated regularly.

What is Thalomid?

Thalomid has active ingredients of thalidomide. It is often used in multiple myeloma. eHealthMe is studying from 38,099 Thalomid users. Check the latest studies of Thalomid.

What is Melaena?

Melaena (the passage of black, tarry stools) is found to be associated with 1,305 drugs and 1,475 conditions by eHealthMe. Check the latest studies of Melaena.

On Aug, 10, 2026

38,055 people reported to have side effects when taking Thalomid.
Among them, 22 people (0.06%) have Melaena.

Among these 22 people:

How long have people been on Thalomid when they have Melaena? *

What is the gender of people who have Melaena when taking Thalomid? *

female: 60 %
male: 40 %

What is the age of people who have Melaena when taking Thalomid? *

What are other drugs people take besides Thalomid? *

What are other side effects people have besides Melaena? *

Anaemia (lack of blood): 7 people, 31.82%
Nausea (feeling of having an urge to vomit): 6 people, 27.27%
Haematemesis (vomiting of blood): 5 people, 22.73%
Dizziness: 5 people, 22.73%
Dehydration (dryness resulting from the removal of water): 4 people, 18.18%
Thrombocytopenia (decrease of platelets in blood): 4 people, 18.18%
Abdominal Discomfort: 3 people, 13.64%
Hypertensive Crisis: 3 people, 13.64%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 3 people, 13.64%
Weakness: 3 people, 13.64%

What are the existing conditions these people have? *

Arteriovenous Malformation: 3 people, 13.64%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 9.09%
Tracheal Cancer (cancer of trachea): 1 person, 4.55%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 4.55%
Oedema (fluid collection in tissue): 1 person, 4.55%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 4.55%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 4.55%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.55%
Fungal Infection: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Thalomid and have Melaena?

- Check whether Melaena is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thalomid:

Thalomid (38,099 reports)

Melaena treatments and more:

Melaena (29,850 reports)

Browse all side effects of Thalomid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Melaena:

Melaena (1,305 drugs)

Browse all the conditions that are associated with Melaena:

Melaena (1,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thalidomide (the active ingredients of Thalomid) and Thalomid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.