Theophylline and Refractory anaemia - a phase IV clinical study of FDA data
Summary:
Refractory anaemia is reported as a side effect among people who take Theophylline (theophylline), especially for people who are female, 60+ old, also take Lisinopril, and have Chronic renal failure.
The phase IV clinical study analyzes which people have Refractory anaemia when taking Theophylline. It is created by eHealthMe based on reports of 18,953 people who have side effects when taking Theophylline from the FDA, and is updated regularly.
What is Theophylline?
Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.
What is Refractory anaemia?
Refractory anaemia (an anaemia which does not respond to treatment) is found to be associated with 65 drugs and 165 conditions by eHealthMe. Check the latest studies of Refractory anaemia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
18,953 people reported to have side effects when taking Theophylline.
Among them, 100 people (0.53%) have Refractory anaemia.

Among these 100 people:
What is the gender of people who have Refractory anaemia when taking Theophylline? *
- female: 98.99 %
- male: 1.01 %
What is the age of people who have Refractory anaemia when taking Theophylline? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
What are other drugs people take besides Theophylline? *
- Lisinopril: 99 people, 99.00%
- Formoterol Fumarate: 98 people, 98.00%
- Furosemide: 98 people, 98.00%
- Allopurinol: 98 people, 98.00%
- Glimepiride: 98 people, 98.00%
- Digoxin: 98 people, 98.00%
- Carvedilol: 98 people, 98.00%
- Simvastatin: 98 people, 98.00%
- Aranesp: 98 people, 98.00%
- Enalapril Maleate: 97 people, 97.00%
What are other side effects people have besides Refractory anaemia? *
- Fatigue (feeling of tiredness): 99 people, 99.00%
- Rectal Haemorrhage (bleeding from anus): 98 people, 98.00%
- Right Ventricular Failure (right half of the heart fails to work): 98 people, 98.00%
- Colonic Polyp (extra part of colon tissue grow in intestine): 98 people, 98.00%
- Cardioactive Drug Level Increased: 98 people, 98.00%
- Muscle Twitching: 98 people, 98.00%
- Hypopnea: 98 people, 98.00%
- Pain: 98 people, 98.00%
- Pleural Effusion (water on the lungs): 98 people, 98.00%
- Aplasia Pure Red Cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 98 people, 98.00%
What are the existing conditions these people have? *
- Chronic Renal Failure (kidney failure): 98 people, 98.00%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 1.00%
- Blood Disorder: 1 person, 1.00%
* Approximation only. Some reports may have incomplete information.
Do you take Theophylline and have Refractory anaemia?
- Check whether Refractory anaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Theophylline:
- Theophylline (19,150 reports)
Refractory anaemia treatments and more:
- Refractory anaemia (646 reports)
How severe was Refractory anaemia and when was it recovered:
Expand to all the drugs that have ingredients of theophylline:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Theophylline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Refractory anaemia:
- Refractory anaemia (65 drugs)
Browse all the conditions that are associated with Refractory anaemia:
- Refractory anaemia (165 conditions)
Related publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline (the active ingredients of Theophylline) and Theophylline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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