Thiamine and Anion gap increased - a phase IV clinical study of FDA data

Summary:

Anion gap increased is reported as a side effect among people who take Thiamine (thiamine (vitamin b1)), especially for people who are male, 60+ old, also take Insulin, and have Pain.

The phase IV clinical study analyzes which people have Anion gap increased when taking Thiamine. It is created by eHealthMe based on reports of 10,941 people who have side effects when taking Thiamine from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,035 Thiamine users. Check the latest studies of Thiamine.

What is Anion gap increased?

Anion gap increased is found to be associated with 254 drugs and 396 conditions by eHealthMe. Check the latest studies of Anion gap increased.

On Jun, 17, 2026

10,941 people reported to have side effects when taking Thiamine.
Among them, 18 people (0.16%) have Anion gap increased.

Could Thiamine cause Anion gap increased?

Among these 18 people:

What is the gender of people who have Anion gap increased when taking Thiamine? *

female: 0.0 %
male: 100 %

What is the age of people who have Anion gap increased when taking Thiamine? *

What are other drugs people take besides Thiamine? *

What are other side effects people have besides Anion gap increased? *

Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 13 people, 72.22%
C-Reactive Protein Increased: 10 people, 55.56%
Confusional State: 10 people, 55.56%
Pyroglutamate Increased: 8 people, 44.44%
Hypotension (abnormally low blood pressure): 6 people, 33.33%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 5 people, 27.78%
Leukocytosis (increased white blood cells): 5 people, 27.78%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 27.78%
Hyperglycemia (high blood sugar): 5 people, 27.78%
Fever: 5 people, 27.78%

What are the existing conditions these people have? *

Pain: 8 people, 44.44%
Type 2 Diabetes: 7 people, 38.89%
Staphylococcal Bacteraemia (a bacterial infection of blood): 5 people, 27.78%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 27.78%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 27.78%
Bacterial Sepsis: 5 people, 27.78%
Stable Angina (a constant chest pain): 4 people, 22.22%
Septic Shock (shock due to blood infection): 4 people, 22.22%
Psychotic Disorder: 4 people, 22.22%
High Blood Pressure: 4 people, 22.22%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Anion gap increased?

- Check whether Anion gap increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiamine:

Thiamine (11,035 reports)

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anion gap increased:

Anion gap increased (254 drugs)

Browse all the conditions that are associated with Anion gap increased:

Anion gap increased (396 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.