Thiamine and Joint stiffness - a phase IV clinical study of FDA data

Summary:

Joint stiffness is reported as a side effect among people who take Thiamine (thiamine (vitamin b1)), especially for people who are female, 40-49 old, also take Calcium, and have Inflammation.

The phase IV clinical study analyzes which people have Joint stiffness when taking Thiamine. It is created by eHealthMe based on reports of 10,941 people who have side effects when taking Thiamine from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

What is Joint stiffness?

Joint stiffness is found to be associated with 1,301 drugs and 1,340 conditions by eHealthMe. Check the latest studies of Joint stiffness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

10,941 people reported to have side effects when taking Thiamine.
Among them, 28 people (0.26%) have Joint stiffness.

Among these 28 people:

What is the gender of people who have Joint stiffness when taking Thiamine? *

female: 67.86 %
male: 32.14 %

What is the age of people who have Joint stiffness when taking Thiamine? *

What are other drugs people take besides Thiamine? *

What are other side effects people have besides Joint stiffness? *

Itching: 24 people, 85.71%
Weakness: 22 people, 78.57%
Pain: 22 people, 78.57%
Joint Pain: 22 people, 78.57%
Fatigue (feeling of tiredness): 22 people, 78.57%
Hyperhidrosis (abnormally increased sweating): 21 people, 75.00%
Hypoaesthesia (reduced sense of touch or sensation): 21 people, 75.00%
Pain In Extremity: 21 people, 75.00%
Haemoglobin Decreased: 17 people, 60.71%
Feeling Of Despair: 17 people, 60.71%

What are the existing conditions these people have? *

Thrombocytopenic Purpura (a bleeding disorder in which the immune system destroys platelets): 10 people, 35.71%
Platelet Count Increased: 10 people, 35.71%
Pain: 10 people, 35.71%
Inflammation: 10 people, 35.71%
Psychotic Disorder: 4 people, 14.29%
Nuclear Magnetic Resonance Imaging Brain: 4 people, 14.29%
Stress And Anxiety: 2 people, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Joint stiffness?

- Check whether Joint stiffness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiamine:

Thiamine (11,036 reports)

Joint stiffness treatments and more:

Joint stiffness (33,165 reports)

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint stiffness:

Joint stiffness (1,301 drugs)

Browse all the conditions that are associated with Joint stiffness:

Joint stiffness (1,340 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.