Thiamine and Oculogyric crisis - a phase IV clinical study of FDA data

Summary:

Oculogyric crisis is reported as a side effect among people who take Thiamine (thiamine (vitamin b1)), especially for people who are female, 20-29 old, also take Prochlorperazine, and have Hyperemesis gravidarum.

The phase IV clinical study analyzes which people have Oculogyric crisis when taking Thiamine. It is created by eHealthMe based on reports of 10,941 people who have side effects when taking Thiamine from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

What is Oculogyric crisis?

Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction) is found to be associated with 156 drugs and 260 conditions by eHealthMe. Check the latest studies of Oculogyric crisis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

10,941 people reported to have side effects when taking Thiamine.
Among them, 11 people (0.1%) have Oculogyric crisis.

Among these 11 people:

What is the gender of people who have Oculogyric crisis when taking Thiamine? *

female: 60 %
male: 40 %

What is the age of people who have Oculogyric crisis when taking Thiamine? *

What are other drugs people take besides Thiamine? *

What are other side effects people have besides Oculogyric crisis? *

Akathisia (a movement disorder characterized by a feeling of inner restlessness): 6 people, 54.55%
Drug Ineffective: 5 people, 45.45%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 36.36%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 4 people, 36.36%
Arrhythmias (irregular heartbeat): 4 people, 36.36%
Maternal Exposure During Pregnancy (use of substance during pregnancy): 4 people, 36.36%
Joint Stiffness: 4 people, 36.36%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 36.36%
Hyperhidrosis (abnormally increased sweating): 4 people, 36.36%
High Blood Pressure: 4 people, 36.36%

What are the existing conditions these people have? *

Hyperemesis Gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance): 5 people, 45.45%
Psychotic Disorder: 4 people, 36.36%
Akathisia (a movement disorder characterized by a feeling of inner restlessness): 4 people, 36.36%
Stress And Anxiety: 2 people, 18.18%
Hyperreflexia (overactive or over responsive reflexes): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Oculogyric crisis?

- Check whether Oculogyric crisis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiamine:

Thiamine (11,036 reports)

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oculogyric crisis:

Oculogyric crisis (156 drugs)

Browse all the conditions that are associated with Oculogyric crisis:

Oculogyric crisis (260 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.