Thiamine and Spinal osteoarthritis - a phase IV clinical study of FDA data

Summary:

Spinal osteoarthritis is reported as a side effect among people who take Thiamine (thiamine (vitamin b1)), especially for people who are female, 60+ old, also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Spinal osteoarthritis when taking Thiamine. It is created by eHealthMe based on reports of 10,941 people who have side effects when taking Thiamine from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

What is Spinal osteoarthritis?

Spinal osteoarthritis (joint cartilage loss in spine) is found to be associated with 1,414 drugs and 1,125 conditions by eHealthMe. Check the latest studies of Spinal osteoarthritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

10,941 people reported to have side effects when taking Thiamine.
Among them, 24 people (0.22%) have Spinal osteoarthritis.

Could Thiamine cause Spinal osteoarthritis?

Among these 24 people:

What is the gender of people who have Spinal osteoarthritis when taking Thiamine? *

female: 60.87 %
male: 39.13 %

What is the age of people who have Spinal osteoarthritis when taking Thiamine? *

What are other drugs people take besides Thiamine? *

What are other side effects people have besides Spinal osteoarthritis? *

Joint Pain: 17 people, 70.83%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 66.67%
High Blood Pressure: 13 people, 54.17%
Nausea (feeling of having an urge to vomit): 13 people, 54.17%
Asthma: 13 people, 54.17%
Stress And Anxiety: 12 people, 50.00%
Oedema Peripheral (superficial swelling): 12 people, 50.00%
Dyspnea (difficult or laboured breathing): 12 people, 50.00%
Pain: 12 people, 50.00%
Pleural Effusion (water on the lungs): 11 people, 45.83%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 9 people, 37.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 37.50%
Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 20.83%
Pain: 2 people, 8.33%
High Blood Pressure: 2 people, 8.33%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 4.17%
Blood Pressure Abnormal: 1 person, 4.17%
Cardiac Failure: 1 person, 4.17%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Spinal osteoarthritis?

- Check whether Spinal osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiamine:

Thiamine (11,036 reports)

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,414 drugs)

Browse all the conditions that are associated with Spinal osteoarthritis:

Spinal osteoarthritis (1,125 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.