Thiamine and Tardive dyskinesia - a phase IV clinical study of FDA data

Summary:

Tardive dyskinesia is reported as a side effect among people who take Thiamine (thiamine (vitamin b1)), especially for people who are male, 60+ old, also take Tiotropium Bromide, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Tardive dyskinesia when taking Thiamine. It is created by eHealthMe based on reports of 10,941 people who have side effects when taking Thiamine from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

What is Tardive dyskinesia?

Tardive dyskinesia (a disorder that involves involuntary movements) is found to be associated with 760 drugs and 1,323 conditions by eHealthMe. Check the latest studies of Tardive dyskinesia.

On Aug, 04, 2026

10,941 people reported to have side effects when taking Thiamine.
Among them, 54 people (0.49%) have Tardive dyskinesia.

Could Thiamine cause Tardive dyskinesia?

Among these 54 people:

What is the gender of people who have Tardive dyskinesia when taking Thiamine? *

female: 21.57 %
male: 78.43 %

What is the age of people who have Tardive dyskinesia when taking Thiamine? *

What are other drugs people take besides Thiamine? *

What are other side effects people have besides Tardive dyskinesia? *

Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 31 people, 57.41%
Movement - Uncontrolled Or Slow: 27 people, 50.00%
Rib Fracture: 26 people, 48.15%
Fall: 26 people, 48.15%
Mastication Disorder (disease of chewing food): 25 people, 46.30%
Aptyalism (deficiency or absence of saliva): 25 people, 46.30%
Muscle Rigidity (muscle stiffness): 25 people, 46.30%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 25 people, 46.30%
Delirium (wild excitement): 24 people, 44.44%
Sarcopenia (loss of muscle mass and strength): 24 people, 44.44%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 12 people, 22.22%
Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 10 people, 18.52%
Insomnia (sleeplessness): 7 people, 12.96%
Pain: 6 people, 11.11%
Peritonitis Bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 5 people, 9.26%
Stress And Anxiety: 1 person, 1.85%
Psychotic Disorder: 1 person, 1.85%
Parkinson's Disease: 1 person, 1.85%
Osteoporosis (bones weak and more likely to break): 1 person, 1.85%
Nausea (feeling of having an urge to vomit): 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Thiamine and have Tardive dyskinesia?

- Check whether Tardive dyskinesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiamine:

Thiamine (11,036 reports)

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tardive dyskinesia:

Tardive dyskinesia (760 drugs)

Browse all the conditions that are associated with Tardive dyskinesia:

Tardive dyskinesia (1,323 conditions)

Related publications that referenced our studies

Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
Manjunatha N, Ganjekar S, Mahendra JV, Kilara N, Srinivasa R, "Tardive Dyskinesia Associated With Anastrozole", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) (the active ingredients of Thiamine) and Thiamine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.