Thiola ec and Cystitis aggravated - a phase IV clinical study of FDA data

Summary:

Cystitis aggravated is reported as a side effect among people who take Thiola ec (tiopronin), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Abilify, and have Cystinuria.

The phase IV clinical study analyzes which people have Cystitis aggravated when taking Thiola ec. It is created by eHealthMe based on reports of 362 people who have side effects when taking Thiola ec from the FDA, and is updated regularly.

What is Thiola ec?

Thiola ec has active ingredients of tiopronin. eHealthMe is studying from 362 Thiola ec users. Check the latest studies of Thiola ec.

What is Cystitis aggravated?

Cystitis aggravated (inflammation of the wall of the bladder) is found to be associated with 1,999 drugs and 766 conditions by eHealthMe. Check the latest studies of Cystitis aggravated.



On Jun, 17, 2026

362 people reported to have side effects when taking Thiola ec.
Among them, 12 people (3.31%) have Cystitis aggravated.

Could Thiola ec cause Cystitis aggravated?

Among these 12 people:

How long have people been on Thiola ec when they have Cystitis aggravated? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cystitis aggravated when taking Thiola ec? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Cystitis aggravated when taking Thiola ec? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 25.0 %
  • 20-29: 8.33 %
  • 30-39: 25.0 %
  • 40-49: 16.67 %
  • 50-59: 8.33 %
  • 60+: 16.67 %

What are other drugs people take besides Thiola ec? *

  1. Zyrtec: 2 people, 16.67%
  2. Sertraline: 2 people, 16.67%
  3. Seroquel: 2 people, 16.67%
  4. Potassium Citrate: 2 people, 16.67%
  5. Omeprazole: 2 people, 16.67%
  6. Abilify: 2 people, 16.67%
  7. Zofran: 1 person, 8.33%
  8. Vitamins: 1 person, 8.33%
  9. Vitamin D: 1 person, 8.33%
  10. Vitamin B12: 1 person, 8.33%

What are other side effects people have besides Cystitis aggravated? *

  1. Drug Ineffective: 6 people, 50.00%
  2. Renal Impairment (severely reduced kidney function): 2 people, 16.67%
  3. Headache (pain in head): 2 people, 16.67%
  4. Fatigue (feeling of tiredness): 2 people, 16.67%
  5. Vision Blurred: 1 person, 8.33%
  6. Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 8.33%
  7. Pain: 1 person, 8.33%
  8. Otitis (ear infection): 1 person, 8.33%
  9. Malaise (a feeling of general discomfort or uneasiness): 1 person, 8.33%
  10. Joint Pain: 1 person, 8.33%

What are the existing conditions these people have? *

  1. Cystinuria (formation of cystine stones in the kidneys, ureter, and bladder): 8 people, 66.67%
  2. Kidney Stones: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thiola ec and have Cystitis aggravated?

- Check whether Cystitis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiola ec:

Cystitis aggravated treatments and more:

How severe was Cystitis aggravated and when was it recovered:

Expand to all the drugs that have ingredients of tiopronin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Thiola ec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cystitis aggravated:

Browse all the conditions that are associated with Cystitis aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on tiopronin (the active ingredients of Thiola ec) and Thiola ec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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