Thiotepa and Left ventricular dysfunction - a phase IV clinical study of FDA data

Summary:

Left ventricular dysfunction is reported as a side effect among people who take Thiotepa (thiotepa), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Etoposide, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Left ventricular dysfunction when taking Thiotepa. It is created by eHealthMe based on reports of 8,095 people who have side effects when taking Thiotepa from the FDA, and is updated regularly.

What is Thiotepa?

Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.

What is Left ventricular dysfunction?

Left ventricular dysfunction is found to be associated with 892 drugs and 792 conditions by eHealthMe. Check the latest studies of Left ventricular dysfunction.

On Jul, 14, 2026

8,095 people reported to have side effects when taking Thiotepa.
Among them, 34 people (0.42%) have Left ventricular dysfunction.

Could Thiotepa cause Left ventricular dysfunction?

Among these 34 people:

How long have people been on Thiotepa when they have Left ventricular dysfunction? *

What is the gender of people who have Left ventricular dysfunction when taking Thiotepa? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Left ventricular dysfunction when taking Thiotepa? *

What are other drugs people take besides Thiotepa? *

What are other side effects people have besides Left ventricular dysfunction? *

Febrile Neutropenia (fever with reduced white blood cells): 17 people, 50.00%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 17 people, 50.00%
Visual Impairment: 16 people, 47.06%
Pain: 16 people, 47.06%
Escherichia Urinary Tract Infection (urinary tract infection by escherichia coli): 16 people, 47.06%
Fever: 16 people, 47.06%
Bone Marrow Failure: 16 people, 47.06%
Hepatotoxicity (chemical-driven liver damage): 16 people, 47.06%
Herpes Zoster: 16 people, 47.06%
Hypokinesia (decreased bodily movement): 16 people, 47.06%

What are the existing conditions these people have? *

Nervous System Disorder (a general class of medical conditions affecting the nervous system): 15 people, 44.12%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 15 people, 44.12%
Medulloblastoma (a fast-growing, high-grade tumour that always begins in the cerebellum): 9 people, 26.47%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 1 person, 2.94%
Oral Candidiasis (fungal infection of mouth): 1 person, 2.94%
Neuropathy Peripheral (surface nerve damage): 1 person, 2.94%
Metastasis (spreadable cancer to other organ from origin): 1 person, 2.94%
Metastases To Bone (cancer spreads to bone): 1 person, 2.94%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 2.94%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Thiotepa and have Left ventricular dysfunction?

- Check whether Left ventricular dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thiotepa:

Thiotepa (8,097 reports)

Browse all side effects of Thiotepa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (892 drugs)

Browse all the conditions that are associated with Left ventricular dysfunction:

Left ventricular dysfunction (792 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on thiotepa (the active ingredients of Thiotepa) and Thiotepa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.