Thorazine and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Thorazine (chlorpromazine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Ativan, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Thorazine. It is created by eHealthMe based on reports of 3,071 people who have side effects when taking Thorazine from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,387 drugs and 655 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

3,071 people reported to have side effects when taking Thorazine.
Among them, 20 people (0.65%) have Angina pectoris aggravated.

Could Thorazine cause Angina pectoris aggravated?

Among these 20 people:

How long have people been on Thorazine when they have Angina pectoris aggravated? *

What is the gender of people who have Angina pectoris aggravated when taking Thorazine? *

female: 30 %
male: 70 %

What is the age of people who have Angina pectoris aggravated when taking Thorazine? *

What are other drugs people take besides Thorazine? *

What are other side effects people have besides Angina pectoris aggravated? *

Cardiac Failure Congestive: 12 people, 60.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 12 people, 60.00%
Agitation (state of anxiety or nervous excitement): 12 people, 60.00%
Stress And Anxiety: 12 people, 60.00%
Neuropathy Peripheral (surface nerve damage): 11 people, 55.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 11 people, 55.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 55.00%
Weakness: 10 people, 50.00%
Pain: 10 people, 50.00%
Cuts And Puncture Wounds: 10 people, 50.00%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 60.00%
High Blood Pressure: 11 people, 55.00%
Pain: 11 people, 55.00%
Stress And Anxiety: 10 people, 50.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 9 people, 45.00%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 9 people, 45.00%
Multiple Myeloma (cancer of the plasma cells): 9 people, 45.00%
Metastases To Bone (cancer spreads to bone): 9 people, 45.00%
Depression: 4 people, 20.00%
Neuralgia (pain in one or more nerves): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Thorazine and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Thorazine:

Thorazine (3,237 reports)

Browse all side effects of Thorazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,387 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (655 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorpromazine hydrochloride (the active ingredients of Thorazine) and Thorazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.