Tiazac and Aortic valve incompetence - a phase IV clinical study of FDA data

Summary:

Aortic valve incompetence is reported as a side effect among people who take Tiazac (diltiazem hydrochloride), especially for people who are female, 60+ old, also take Lipitor, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Aortic valve incompetence when taking Tiazac. It is created by eHealthMe based on reports of 4,624 people who have side effects when taking Tiazac from the FDA, and is updated regularly.

What is Tiazac?

Tiazac has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 4,761 Tiazac users. Check the latest studies of Tiazac.

What is Aortic valve incompetence?

Aortic valve incompetence is found to be associated with 923 drugs and 880 conditions by eHealthMe. Check the latest studies of Aortic valve incompetence.

On Jul, 05, 2026

4,624 people reported to have side effects when taking Tiazac.
Among them, 16 people (0.35%) have Aortic valve incompetence.

Could Tiazac cause Aortic valve incompetence?

Among these 16 people:

What is the gender of people who have Aortic valve incompetence when taking Tiazac? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Aortic valve incompetence when taking Tiazac? *

What are other drugs people take besides Tiazac? *

Vioxx: 7 people, 43.75%
Lipitor: 7 people, 43.75%
Prevacid: 6 people, 37.50%
Lasix: 5 people, 31.25%
Aspirin: 5 people, 31.25%
Plavix: 4 people, 25.00%
Prilosec: 4 people, 25.00%
Advil: 4 people, 25.00%
Omega-3 Marine Triglycerides: 3 people, 18.75%
Nexium: 3 people, 18.75%

What are other side effects people have besides Aortic valve incompetence? *

Tricuspid Valve Incompetence (inefficient heart valve): 12 people, 75.00%
Mitral Valve Incompetence (inefficient heart valve): 12 people, 75.00%
Cardiac Failure Congestive: 9 people, 56.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 50.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 8 people, 50.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 8 people, 50.00%
Heart Attack: 8 people, 50.00%
Weakness: 7 people, 43.75%
Anaemia (lack of blood): 7 people, 43.75%
Aortic Valve Sclerosis (narrowing of the aortic valve): 7 people, 43.75%

What are the existing conditions these people have? *

Asthma: 4 people, 25.00%
High Blood Cholesterol: 4 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 18.75%
Osteoporosis (bones weak and more likely to break): 3 people, 18.75%
Muscle Spasms (muscle contraction): 3 people, 18.75%
Lung Disorder (lung disease): 3 people, 18.75%
Cardiac Failure Congestive: 3 people, 18.75%
Gout (uric acid crystals building up in the body): 3 people, 18.75%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 18.75%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Tiazac and have Aortic valve incompetence?

- Check whether Aortic valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tiazac:

Tiazac (4,761 reports)

Browse all side effects of Tiazac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic valve incompetence:

Aortic valve incompetence (923 drugs)

Browse all the conditions that are associated with Aortic valve incompetence:

Aortic valve incompetence (880 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride (the active ingredients of Tiazac) and Tiazac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.