Tikosyn and Exercise tolerance decreased - a phase IV clinical study of FDA data

Summary:

Exercise tolerance decreased is reported as a side effect among people who take Tikosyn (dofetilide), especially for people who are male, 40-49 old, also take Lasix, and have Atrial tachycardia.

The phase IV clinical study analyzes which people have Exercise tolerance decreased when taking Tikosyn. It is created by eHealthMe based on reports of 11,814 people who have side effects when taking Tikosyn from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Exercise tolerance decreased?

Exercise tolerance decreased is found to be associated with 626 drugs and 724 conditions by eHealthMe. Check the latest studies of Exercise tolerance decreased.

On Jul, 19, 2026

11,814 people reported to have side effects when taking Tikosyn.
Among them, 16 people (0.14%) have Exercise tolerance decreased.

Could Tikosyn cause Exercise tolerance decreased?

Among these 16 people:

What is the gender of people who have Exercise tolerance decreased when taking Tikosyn? *

female: 12.5 %
male: 87.5 %

What is the age of people who have Exercise tolerance decreased when taking Tikosyn? *

What are other drugs people take besides Tikosyn? *

What are other side effects people have besides Exercise tolerance decreased? *

Cardiac Failure Congestive: 12 people, 75.00%
Fatigue (feeling of tiredness): 12 people, 75.00%
Sleep Apnea Syndrome: 11 people, 68.75%
Cardiac Failure: 10 people, 62.50%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 10 people, 62.50%
Cholecystitis Acute (rapid infection of gallbladder): 10 people, 62.50%
Aortic Valve Calcification: 10 people, 62.50%
Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 9 people, 56.25%
Pulmonary Arterial Pressure Increased: 9 people, 56.25%
Hypotension (abnormally low blood pressure): 9 people, 56.25%

What are the existing conditions these people have? *

Atrial Tachycardia (rhythm disturbance that arises in the atria): 2 people, 12.50%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.25%
Sinus Rhythm (normal beating of the heart): 1 person, 6.25%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 1 person, 6.25%
Irritable Bowel Syndrome: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Tikosyn and have Exercise tolerance decreased?

- Check whether Exercise tolerance decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tikosyn:

Tikosyn (12,202 reports)

Browse all side effects of Tikosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (626 drugs)

Browse all the conditions that are associated with Exercise tolerance decreased:

Exercise tolerance decreased (724 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dofetilide (the active ingredients of Tikosyn) and Tikosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.