Tikosyn and Irritable bowel syndrome - a phase IV clinical study of FDA data

Summary:

Irritable bowel syndrome is reported as a side effect among people who take Tikosyn (dofetilide), especially for people who are female, 60+ old, also take Metronidazole, and have High blood pressure.

The phase IV clinical study analyzes which people have Irritable bowel syndrome when taking Tikosyn. It is created by eHealthMe based on reports of 11,814 people who have side effects when taking Tikosyn from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Irritable bowel syndrome?

Irritable bowel syndrome is found to be associated with 1,317 drugs and 2,122 conditions by eHealthMe. Check the latest studies of Irritable bowel syndrome.

On Jul, 16, 2026

11,814 people reported to have side effects when taking Tikosyn.
Among them, 11 people (0.09%) have Irritable bowel syndrome.

Could Tikosyn cause Irritable bowel syndrome?

Among these 11 people:

What is the gender of people who have Irritable bowel syndrome when taking Tikosyn? *

female: 63.64 %
male: 36.36 %

What is the age of people who have Irritable bowel syndrome when taking Tikosyn? *

What are other drugs people take besides Tikosyn? *

What are other side effects people have besides Irritable bowel syndrome? *

Extrasystoles: 3 people, 27.27%
Stress And Anxiety: 3 people, 27.27%
Infection: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Insomnia (sleeplessness): 2 people, 18.18%
Heart Rate Irregular: 2 people, 18.18%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 2 people, 18.18%
Urinary Tract Infection: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%

What are the existing conditions these people have? *

Infection: 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
High Blood Cholesterol: 1 person, 9.09%
Heart Rate Irregular: 1 person, 9.09%
Heart Rate Increased: 1 person, 9.09%
Cardiac Disorder: 1 person, 9.09%
Blood Disorder: 1 person, 9.09%
Bleeding Disorders: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tikosyn and have Irritable bowel syndrome?

- Check whether Irritable bowel syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tikosyn:

Tikosyn (12,202 reports)

Browse all side effects of Tikosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (1,317 drugs)

Browse all the conditions that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (2,122 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dofetilide (the active ingredients of Tikosyn) and Tikosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.