Timoptic-xe and Fatigue - a phase IV clinical study of FDA data
Summary:
Fatigue is reported as a side effect among people who take Timoptic-xe (timolol maleate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Tricor, and have High blood cholesterol.
The phase IV clinical study analyzes which people have Fatigue when taking Timoptic-xe. It is created by eHealthMe based on reports of 480 people who have side effects when taking Timoptic-xe from the FDA, and is updated regularly.
What is Timoptic-xe?
Timoptic-xe has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 488 Timoptic-xe users. Check the latest studies of Timoptic-xe.
What is Fatigue?
Fatigue (feeling of tiredness) is found to be associated with 4,027 drugs and 6,379 conditions by eHealthMe. Check the latest studies of Fatigue.
480 people reported to have side effects when taking Timoptic-xe.
Among them, 28 people (5.83%) have Fatigue.

Among these 28 people:
How long have people been on Timoptic-xe when they have Fatigue? *
- < 1 month: 50 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 50 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Fatigue when taking Timoptic-xe? *
- female: 46.43 %
- male: 53.57 %
What is the age of people who have Fatigue when taking Timoptic-xe? *
- 0-1: 0.0 %
- 2-9: 3.7 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 18.52 %
- 50-59: 25.93 %
- 60+: 51.85 %
What are other drugs people take besides Timoptic-xe? *
- Xalatan: 6 people, 21.43%
- Prednisone: 6 people, 21.43%
- Tricor: 6 people, 21.43%
- Zocor: 5 people, 17.86%
- Precose: 4 people, 14.29%
- Rezulin: 4 people, 14.29%
- Betagan: 4 people, 14.29%
- Baclofen: 4 people, 14.29%
- Glucotrol Xl: 4 people, 14.29%
- Premarin: 4 people, 14.29%
What are other side effects people have besides Fatigue? *
- Weakness: 11 people, 39.29%
- High Blood Cholesterol: 8 people, 28.57%
- Joint Pain: 7 people, 25.00%
- Pain: 7 people, 25.00%
- Indigestion: 6 people, 21.43%
- Nausea (feeling of having an urge to vomit): 5 people, 17.86%
- Chest Pain: 5 people, 17.86%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.86%
- Weight Decreased: 5 people, 17.86%
- Tricuspid Valve Incompetence (inefficient heart valve): 5 people, 17.86%
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 14.29%
- High Blood Cholesterol: 4 people, 14.29%
- Diabetes: 3 people, 10.71%
- Back Pain: 2 people, 7.14%
- Ill-Defined Disorder: 2 people, 7.14%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 7.14%
- Sleep Apnea Syndrome: 1 person, 3.57%
- Drug Hypersensitivity: 1 person, 3.57%
- Breast Cancer: 1 person, 3.57%
- Cardiac Failure Congestive: 1 person, 3.57%
* Approximation only. Some reports may have incomplete information.
Do you take Timoptic-xe and have Fatigue?
- Check whether Fatigue is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Timoptic-xe:
- Timoptic-xe (488 reports)
Fatigue treatments and more:
- Fatigue (967,537 reports)
How severe was Fatigue and when was it recovered:
Expand to all the drugs that have ingredients of timolol maleate:
- Fatigue and drugs with ingredients of timolol maleate (1,099 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Timoptic-xe:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Fatigue:
- Fatigue (4,027 drugs)
Browse all the conditions that are associated with Fatigue:
- Fatigue (6,379 conditions)
Related publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on timolol maleate (the active ingredients of Timoptic-xe) and Timoptic-xe (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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