Tizanidine hydrochloride and Injection site reaction - a phase IV clinical study of FDA data

Summary:

Injection site reaction is reported as a side effect among people who take Tizanidine hydrochloride (tizanidine hydrochloride), especially for people who are female, 40-49 old, also take Baclofen, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Injection site reaction when taking Tizanidine hydrochloride. It is created by eHealthMe based on reports of 6,179 people who have side effects when taking Tizanidine hydrochloride from the FDA, and is updated regularly.

What is Tizanidine hydrochloride?

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 7,448 Tizanidine hydrochloride users. Check the latest studies of Tizanidine hydrochloride.

What is Injection site reaction?

Injection site reaction is found to be associated with 1,169 drugs and 1,064 conditions by eHealthMe. Check the latest studies of Injection site reaction.

On Nov, 20, 2025

6,179 people reported to have side effects when taking Tizanidine hydrochloride.
Among them, 15 people (0.24%) have Injection site reaction.

Could Tizanidine hydrochloride cause Injection site reaction?

Among these 15 people:

What is the gender of people who have Injection site reaction when taking Tizanidine hydrochloride? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Injection site reaction when taking Tizanidine hydrochloride? *

What are other drugs people take besides Tizanidine hydrochloride? *

Baclofen: 6 people, 40.00%
Plegridy: 4 people, 26.67%
Enbrel: 3 people, 20.00%
Singulair: 3 people, 20.00%
Spiriva: 2 people, 13.33%
Bupropion Hydrochloride: 2 people, 13.33%
Neurontin: 2 people, 13.33%
Proair Hfa: 2 people, 13.33%
Lyrica: 2 people, 13.33%
Symbicort: 2 people, 13.33%

What are other side effects people have besides Injection site reaction? *

Injection Site Pain: 6 people, 40.00%
Injection Site Pruritus (severe itching at injection site): 4 people, 26.67%
Injection Site Urticaria (rash of round, red welts on the skin at injection site): 3 people, 20.00%
Injection Site Haemorrhage (bleeding from injection site): 3 people, 20.00%
Injection Site Erythema (redness at injection site): 3 people, 20.00%
Hepatic Enzyme Increased: 2 people, 13.33%
Injection Site Rash: 2 people, 13.33%
Influenza Like Illness: 2 people, 13.33%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 26.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 6.67%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.67%
Migraine (headache): 1 person, 6.67%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 6.67%
Alcoholism (problems with alcohol): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Tizanidine hydrochloride and have Injection site reaction?

- Check whether Injection site reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tizanidine hydrochloride:

Tizanidine hydrochloride (7,448 reports)

Browse all side effects of Tizanidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site reaction:

Injection site reaction (1,169 drugs)

Browse all the conditions that are associated with Injection site reaction:

Injection site reaction (1,064 conditions)

Drugs similar to Tizanidine hydrochloride and Injection site reaction :

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride (the active ingredients of Tizanidine hydrochloride) and Tizanidine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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