Tizanidine hydrochloride and Respiratory acidosis - a phase IV clinical study of FDA data

Summary:

Respiratory acidosis is reported as a side effect among people who take Tizanidine hydrochloride (tizanidine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Prednisone, and have Myasthenia gravis.

The phase IV clinical study analyzes which people have Respiratory acidosis when taking Tizanidine hydrochloride. It is created by eHealthMe based on reports of 6,179 people who have side effects when taking Tizanidine hydrochloride from the FDA, and is updated regularly.

What is Tizanidine hydrochloride?

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 7,453 Tizanidine hydrochloride users. Check the latest studies of Tizanidine hydrochloride.

What is Respiratory acidosis?

Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease) is found to be associated with 2,242 drugs and 3,540 conditions by eHealthMe. Check the latest studies of Respiratory acidosis.

On Jul, 11, 2026

6,179 people reported to have side effects when taking Tizanidine hydrochloride.
Among them, 34 people (0.55%) have Respiratory acidosis.

Could Tizanidine hydrochloride cause Respiratory acidosis?

Among these 34 people:

How long have people been on Tizanidine hydrochloride when they have Respiratory acidosis? *

What is the gender of people who have Respiratory acidosis when taking Tizanidine hydrochloride? *

female: 71.88 %
male: 28.12 %

What is the age of people who have Respiratory acidosis when taking Tizanidine hydrochloride? *

What are other drugs people take besides Tizanidine hydrochloride? *

Prednisone: 12 people, 35.29%
Gabapentin: 11 people, 32.35%
Acetaminophen: 8 people, 23.53%
Vitamin D3: 8 people, 23.53%
Cyanocobalamin: 8 people, 23.53%
Furosemide: 8 people, 23.53%
Hydroxyzine Hydrochloride: 8 people, 23.53%
Magnesium: 8 people, 23.53%
Potassium Chloride: 8 people, 23.53%
Sodium Chloride: 8 people, 23.53%

What are other side effects people have besides Respiratory acidosis? *

Pneumonia: 11 people, 32.35%
Dyspnea (difficult or laboured breathing): 10 people, 29.41%
Fatigue (feeling of tiredness): 10 people, 29.41%
Hypotension (abnormally low blood pressure): 10 people, 29.41%
Weakness: 9 people, 26.47%
Nausea (feeling of having an urge to vomit): 8 people, 23.53%
Urinary Tract Infection: 7 people, 20.59%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 7 people, 20.59%
Stress And Anxiety: 7 people, 20.59%
Weight Increased: 6 people, 17.65%

What are the existing conditions these people have? *

Asthma: 4 people, 11.76%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 4 people, 11.76%
Diarrhea: 3 people, 8.82%
High Blood Pressure: 3 people, 8.82%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.82%
Type 2 Diabetes: 2 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.88%
Depression: 2 people, 5.88%
Herpes Zoster: 2 people, 5.88%
Hypokalemia (low potassium): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Tizanidine hydrochloride and have Respiratory acidosis?

- Check whether Respiratory acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tizanidine hydrochloride:

Tizanidine hydrochloride (7,453 reports)

Browse all side effects of Tizanidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory acidosis:

Respiratory acidosis (2,242 drugs)

Browse all the conditions that are associated with Respiratory acidosis:

Respiratory acidosis (3,540 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride (the active ingredients of Tizanidine hydrochloride) and Tizanidine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.