Tobi and Insomnia - a phase IV clinical study of FDA data
Summary:
Insomnia is reported as a side effect among people who take Tobi (tobramycin), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Pulmozyme, and have Cystic fibrosis.
The phase IV clinical study analyzes which people have Insomnia when taking Tobi. It is created by eHealthMe based on reports of 9,996 people who have side effects when taking Tobi from the FDA, and is updated regularly.
What is Tobi?
Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.
What is Insomnia?
Insomnia (sleeplessness) is found to be associated with 3,118 drugs and 5,169 conditions by eHealthMe. Check the latest studies of Insomnia.
9,996 people reported to have side effects when taking Tobi.
Among them, 91 people (0.91%) have Insomnia.

Among these 91 people:
How long have people been on Tobi when they have Insomnia? *
- < 1 month: 91.3 %
- 1 - 6 months: 4.35 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 4.35 %
What is the gender of people who have Insomnia when taking Tobi? *
- female: 64.04 %
- male: 35.96 %
What is the age of people who have Insomnia when taking Tobi? *
- 0-1: 0.0 %
- 2-9: 2.86 %
- 10-19: 1.43 %
- 20-29: 20.0 %
- 30-39: 34.29 %
- 40-49: 5.71 %
- 50-59: 11.43 %
- 60+: 24.29 %
What are other drugs people take besides Tobi? *
- Pulmozyme: 50 people, 54.95%
- Cayston: 45 people, 49.45%
- Creon: 34 people, 37.36%
- Zithromax: 25 people, 27.47%
- Trikafta: 24 people, 26.37%
- Singulair: 22 people, 24.18%
- Humalog: 18 people, 19.78%
- Lantus: 18 people, 19.78%
- Qvar: 17 people, 18.68%
- Orkambi: 16 people, 17.58%
What are other side effects people have besides Insomnia? *
- Cough: 26 people, 28.57%
- Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 26 people, 28.57%
- Dyspnea (difficult or laboured breathing): 25 people, 27.47%
- Chest Pain: 25 people, 27.47%
- Stress And Anxiety: 23 people, 25.27%
- Weight Decreased: 19 people, 20.88%
- Fever: 16 people, 17.58%
- Weakness: 16 people, 17.58%
- Coughing Up Blood: 16 people, 17.58%
- Fatigue (feeling of tiredness): 16 people, 17.58%
What are the existing conditions these people have? *
- Cystic Fibrosis (disease of the secretary glands): 65 people, 71.43%
- Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 27 people, 29.67%
- High Blood Pressure: 19 people, 20.88%
- Asthma: 18 people, 19.78%
- Pain: 16 people, 17.58%
- Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 16 people, 17.58%
- Cough: 12 people, 13.19%
- Rickets (softening of bones): 12 people, 13.19%
- Constipation: 11 people, 12.09%
- Fungal Infection: 10 people, 10.99%
* Approximation only. Some reports may have incomplete information.
Do you take Tobi and have Insomnia?
- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tobi:
- Tobi (10,011 reports)
Insomnia treatments and more:
- Insomnia (438,078 reports)
How severe was Insomnia and when was it recovered:
Expand to all the drugs that have ingredients of tobramycin:
- Insomnia and drugs with ingredients of tobramycin (139 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tobi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Insomnia:
- Insomnia (3,118 drugs)
Browse all the conditions that are associated with Insomnia:
- Insomnia (5,169 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on tobramycin (the active ingredients of Tobi) and Tobi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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