Tofacitinib and Wrist deformity - a phase IV clinical study of FDA data

Summary:

Wrist deformity is reported as a side effect among people who take Tofacitinib (tofacitinib), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Orencia, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Wrist deformity when taking Tofacitinib. It is created by eHealthMe based on reports of 5,544 people who have side effects when taking Tofacitinib from the FDA, and is updated regularly.

What is Tofacitinib?

Tofacitinib has active ingredients of tofacitinib. eHealthMe is studying from 5,554 Tofacitinib users. Check the latest studies of Tofacitinib.

What is Wrist deformity?

Wrist deformity is found to be associated with 117 drugs and 160 conditions by eHealthMe. Check the latest studies of Wrist deformity.



On Jul, 17, 2026

5,544 people reported to have side effects when taking Tofacitinib.
Among them, 79 people (1.42%) have Wrist deformity.

Could Tofacitinib cause Wrist deformity?

Among these 79 people:

How long have people been on Tofacitinib when they have Wrist deformity? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Wrist deformity when taking Tofacitinib? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Wrist deformity when taking Tofacitinib? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 98.31 %
  • 60+: 1.69 %

What are other drugs people take besides Tofacitinib? *

  1. Xeljanz: 78 people, 98.73%
  2. Enbrel: 78 people, 98.73%
  3. Orencia: 78 people, 98.73%
  4. Actemra: 68 people, 86.08%
  5. Humira: 67 people, 84.81%
  6. Arava: 67 people, 84.81%
  7. Lyrica: 66 people, 83.54%
  8. Celebrex: 65 people, 82.28%
  9. Diclofenac: 60 people, 75.95%
  10. Naprosyn: 55 people, 69.62%

What are other side effects people have besides Wrist deformity? *

  1. Joint Pain: 68 people, 86.08%
  2. Swelling: 68 people, 86.08%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 68 people, 86.08%
  4. Drug Ineffective: 68 people, 86.08%
  5. Pain: 68 people, 86.08%
  6. Weakness: 67 people, 84.81%
  7. Muscle Spasms (muscle contraction): 67 people, 84.81%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 67 people, 84.81%
  9. Drug Intolerance (drug sensitivity): 67 people, 84.81%
  10. Malaise (a feeling of general discomfort or uneasiness): 67 people, 84.81%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 79 people, 100.00%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 60 people, 75.95%

* Approximation only. Some reports may have incomplete information.

Do you take Tofacitinib and have Wrist deformity?

- Check whether Wrist deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tofacitinib:

Wrist deformity treatments and more:

How severe was Wrist deformity and when was it recovered:

Expand to all the drugs that have ingredients of tofacitinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tofacitinib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Wrist deformity:

Browse all the conditions that are associated with Wrist deformity:


How the study uses the data?

The study uses data from the FDA. It is based on tofacitinib (the active ingredients of Tofacitinib) and Tofacitinib (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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