Tolbutamide and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Tolbutamide (tolbutamide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Atacand, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Headache when taking Tolbutamide. It is created by eHealthMe based on reports of 736 people who have side effects when taking Tolbutamide from the FDA, and is updated regularly.

What is Tolbutamide?

Tolbutamide has active ingredients of tolbutamide. It is often used in diabetes. eHealthMe is studying from 739 Tolbutamide users. Check the latest studies of Tolbutamide.

What is Headache?

Headache (pain in head) is found to be associated with 3,746 drugs and 5,768 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 10, 2026

736 people reported to have side effects when taking Tolbutamide.
Among them, 16 people (2.17%) have Headache.

Among these 16 people:

How long have people been on Tolbutamide when they have Headache? *

What is the gender of people who have Headache when taking Tolbutamide? *

female: 90 %
male: 10 %

What is the age of people who have Headache when taking Tolbutamide? *

What are other drugs people take besides Tolbutamide? *

What are other side effects people have besides Headache? *

Abdominal Pain Upper: 12 people, 75.00%
Infection: 11 people, 68.75%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 11 people, 68.75%
Joint Pain: 11 people, 68.75%
Weight Decreased: 11 people, 68.75%
Ill-Defined Disorder: 11 people, 68.75%
Hypotension (abnormally low blood pressure): 11 people, 68.75%
High Blood Pressure: 11 people, 68.75%
Hepatic Steatosis (fatty liver disease): 11 people, 68.75%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 11 people, 68.75%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 75.00%
Pain: 7 people, 43.75%
Skin Ulcer: 2 people, 12.50%
Metastases To Bone (cancer spreads to bone): 1 person, 6.25%
High Blood Cholesterol: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Tolbutamide and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tolbutamide:

Tolbutamide (739 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Tolbutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,746 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,768 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tolbutamide (the active ingredients of Tolbutamide) and Tolbutamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.