Topiramate and Hypohidrosis - a phase IV clinical study of FDA data

Summary:

Hypohidrosis is reported as a side effect among people who take Topiramate (topiramate), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Carbamazepine, and have Complex partial seizures.

The phase IV clinical study analyzes which people have Hypohidrosis when taking Topiramate. It is created by eHealthMe based on reports of 48,099 people who have side effects when taking Topiramate from the FDA, and is updated regularly.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 49,809 Topiramate users. Check the latest studies of Topiramate.

What is Hypohidrosis?

Hypohidrosis (lack of sweating) is found to be associated with 61 drugs and 176 conditions by eHealthMe. Check the latest studies of Hypohidrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

48,099 people reported to have side effects when taking Topiramate.
Among them, 55 people (0.11%) have Hypohidrosis.

Among these 55 people:

How long have people been on Topiramate when they have Hypohidrosis? *

What is the gender of people who have Hypohidrosis when taking Topiramate? *

female: 58.97 %
male: 41.03 %

What is the age of people who have Hypohidrosis when taking Topiramate? *

What are other drugs people take besides Topiramate? *

What are other side effects people have besides Hypohidrosis? *

Fever: 22 people, 40.00%
Headache (pain in head): 18 people, 32.73%
Weakness: 13 people, 23.64%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 11 people, 20.00%
Corneal Abrasion (loss of the surface of cornea): 11 people, 20.00%
Fatigue (feeling of tiredness): 9 people, 16.36%
Dry Skin: 9 people, 16.36%
Rashes (redness): 8 people, 14.55%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 12.73%
Temperature Intolerance (inability to go in temperature): 6 people, 10.91%

What are the existing conditions these people have? *

Complex Partial Seizures (epileptic seizure): 15 people, 27.27%
Pseudotumor Cerebri (increased pressure within the brain in the absence of a tumour): 3 people, 5.45%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 5.45%
Essential Tremor: 3 people, 5.45%
Depression: 2 people, 3.64%
Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 3.64%
Myoclonic Epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs): 2 people, 3.64%
Infantile Spasms: 2 people, 3.64%
The Flu (the flu is caused by an influenza virus): 1 person, 1.82%
Bipolar Disorder (mood disorder): 1 person, 1.82%

* Approximation only. Some reports may have incomplete information.

Do you take Topiramate and have Hypohidrosis?

- Check whether Hypohidrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Topiramate:

Topiramate (49,809 reports)

Hypohidrosis treatments and more:

Hypohidrosis (557 reports)

Browse all side effects of Topiramate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypohidrosis:

Hypohidrosis (61 drugs)

Browse all the conditions that are associated with Hypohidrosis:

Hypohidrosis (176 conditions)

Related publications that referenced our studies

Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topiramate) and Topiramate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.