Topiramate and Uveitis - a phase IV clinical study of FDA data

Summary:

Uveitis is reported as a side effect among people who take Topiramate (topiramate), especially for people who are female, 30-39 old, have been taking the drug for 5 - 10 years also take Gabapentin, and have Depression.

The phase IV clinical study analyzes which people have Uveitis when taking Topiramate. It is created by eHealthMe based on reports of 48,099 people who have side effects when taking Topiramate from the FDA, and is updated regularly.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 49,809 Topiramate users. Check the latest studies of Topiramate.

What is Uveitis?

Uveitis (inflammation of the uvea) is found to be associated with 830 drugs and 1,529 conditions by eHealthMe. Check the latest studies of Uveitis.



On Apr, 29, 2026

48,099 people reported to have side effects when taking Topiramate.
Among them, 83 people (0.17%) have Uveitis.

Could Topiramate cause Uveitis?

Among these 83 people:

How long have people been on Topiramate when they have Uveitis? *

  • < 1 month: 16.67 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 83.33 %
  • 10+ years: 0.0 %

What is the gender of people who have Uveitis when taking Topiramate? *

  • female: 67.11 %
  • male: 32.89 %

What is the age of people who have Uveitis when taking Topiramate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.43 %
  • 20-29: 7.14 %
  • 30-39: 32.86 %
  • 40-49: 25.71 %
  • 50-59: 30.0 %
  • 60+: 2.86 %

What are other drugs people take besides Topiramate? *

  1. Humira: 6 people, 7.23%
  2. Gabapentin: 6 people, 7.23%
  3. Primidone: 4 people, 4.82%
  4. Lamictal: 4 people, 4.82%
  5. Wellbutrin: 3 people, 3.61%
  6. Armour Thyroid: 3 people, 3.61%
  7. Hydroxyzine: 3 people, 3.61%
  8. Elmiron: 3 people, 3.61%
  9. Cellcept: 3 people, 3.61%
  10. Synthroid: 2 people, 2.41%

What are other side effects people have besides Uveitis? *

  1. Angle Closure Glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity): 39 people, 46.99%
  2. Choroidal Detachment (separation of vascular layer of the eye): 17 people, 20.48%
  3. Choroidal Effusion (fluid collection in vascular layer of eye that nourishes retina): 16 people, 19.28%
  4. Corneal Oedema (corneal swelling): 11 people, 13.25%
  5. Cataract (clouding of the lens inside the eye): 11 people, 13.25%
  6. Hypopyon (pus in the eye): 10 people, 12.05%
  7. Headache (pain in head): 9 people, 10.84%
  8. Blindness: 8 people, 9.64%
  9. Iridocyclitis (inflammation of the iris and ciliary body of the eye): 7 people, 8.43%
  10. Vision Blurred: 7 people, 8.43%

What are the existing conditions these people have? *

  1. Depression: 10 people, 12.05%
  2. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.02%
  3. Binge Eating (pattern of disordered eating which consists of episodes of uncontrollable eating): 5 people, 6.02%
  4. Bipolar Disorder (mood disorder): 5 people, 6.02%
  5. High Blood Cholesterol: 4 people, 4.82%
  6. Weight Decreased: 3 people, 3.61%
  7. Stress And Anxiety: 3 people, 3.61%
  8. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 3.61%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 3.61%
  10. Cystitis Interstitial (unknown cause characterized by bladder pain): 3 people, 3.61%

* Approximation only. Some reports may have incomplete information.

Do you take Topiramate and have Uveitis?

- Check whether Uveitis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Topiramate:

Uveitis treatments and more:

How severe was Uveitis and when was it recovered:

Expand to all the drugs that have ingredients of topiramate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Topiramate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uveitis:

Browse all the conditions that are associated with Uveitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topiramate) and Topiramate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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