Topotecan and Red blood cell count decreased - a phase IV clinical study of FDA data

Summary:

Red blood cell count decreased is reported as a side effect among people who take Topotecan (topotecan hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neulasta, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Red blood cell count decreased when taking Topotecan. It is created by eHealthMe based on reports of 5,841 people who have side effects when taking Topotecan from the FDA, and is updated regularly.

What is Topotecan?

Topotecan has active ingredients of topotecan hydrochloride. eHealthMe is studying from 5,853 Topotecan users. Check the latest studies of Topotecan.

What is Red blood cell count decreased?

Red blood cell count decreased is found to be associated with 1,496 drugs and 1,959 conditions by eHealthMe. Check the latest studies of Red blood cell count decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

5,841 people reported to have side effects when taking Topotecan.
Among them, 15 people (0.26%) have Red blood cell count decreased.

Could Topotecan cause Red blood cell count decreased?

Among these 15 people:

How long have people been on Topotecan when they have Red blood cell count decreased? *

What is the gender of people who have Red blood cell count decreased when taking Topotecan? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Red blood cell count decreased when taking Topotecan? *

What are other drugs people take besides Topotecan? *

What are other side effects people have besides Red blood cell count decreased? *

Haemoglobin Decreased: 8 people, 53.33%
White Blood Cell Count Decreased: 8 people, 53.33%
Thrombocytopenia (decrease of platelets in blood): 8 people, 53.33%
Haematocrit Decreased: 7 people, 46.67%
Nausea And Vomiting: 5 people, 33.33%
Fatigue (feeling of tiredness): 4 people, 26.67%
Monocyte Count Increased: 3 people, 20.00%
Red Cell Distribution Width Increased: 3 people, 20.00%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 20.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 13.33%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Ovarian Cancer (cancer of ovary): 3 people, 20.00%
Pain: 2 people, 13.33%
Lung Cancer - Small Cell (lung cancer): 2 people, 13.33%
Menopause (end of monthly cycles in women): 1 person, 6.67%
Anaemia (lack of blood): 1 person, 6.67%
Anaemia Of Malignant Disease: 1 person, 6.67%
Anaesthesia: 1 person, 6.67%
Birth Control: 1 person, 6.67%
Blood Pressure Abnormal: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Topotecan and have Red blood cell count decreased?

- Check whether Red blood cell count decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Topotecan:

Topotecan (5,853 reports)

Browse all side effects of Topotecan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Red blood cell count decreased:

Red blood cell count decreased (1,496 drugs)

Browse all the conditions that are associated with Red blood cell count decreased:

Red blood cell count decreased (1,959 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on topotecan hydrochloride (the active ingredients of Topotecan) and Topotecan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.