Toprol-xl and Flushing aggravated - a phase IV clinical study of FDA data

Summary:

Flushing aggravated is reported as a side effect among people who take Toprol-xl (metoprolol succinate), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Niaspan, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Flushing aggravated when taking Toprol-xl. It is created by eHealthMe based on reports of 38,273 people who have side effects when taking Toprol-xl from the FDA, and is updated regularly.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

What is Flushing aggravated?

Flushing aggravated (the warm, red condition of human skin) is found to be associated with 1,455 drugs and 459 conditions by eHealthMe. Check the latest studies of Flushing aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

38,273 people reported to have side effects when taking Toprol-xl.
Among them, 695 people (1.82%) have Flushing aggravated.

Could Toprol-xl cause Flushing aggravated?

Among these 695 people:

How long have people been on Toprol-xl when they have Flushing aggravated? *

Click here to view more results

What is the gender of people who have Flushing aggravated when taking Toprol-xl? *

Click here to view

* Approximation only. Some reports may have incomplete information.

Do you take Toprol-xl and have Flushing aggravated?

- Check whether Flushing aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Toprol-xl:

Toprol-xl (40,636 reports)

Flushing aggravated treatments and more:

Flushing aggravated (32 reports)

How severe was Flushing aggravated and when was it recovered:

Flushing aggravated in Toprol-xl

Expand to all the drugs that have ingredients of metoprolol succinate:

Flushing aggravated and drugs with ingredients of metoprolol succinate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Toprol-xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flushing aggravated:

Flushing aggravated (1,455 drugs)

Browse all the conditions that are associated with Flushing aggravated:

Flushing aggravated (459 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Toprol-xl) and Toprol-xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.