Toprol-xl and Thrombophlebitis - a phase IV clinical study of FDA data
Summary:
Thrombophlebitis is reported as a side effect among people who take Toprol-xl (metoprolol succinate), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Birth control.
The phase IV clinical study analyzes which people have Thrombophlebitis when taking Toprol-xl. It is created by eHealthMe based on reports of 38,273 people who have side effects when taking Toprol-xl from the FDA, and is updated regularly.
What is Toprol-xl?
Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.
What is Thrombophlebitis?
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot) is found to be associated with 941 drugs and 1,267 conditions by eHealthMe. Check the latest studies of Thrombophlebitis.
38,273 people reported to have side effects when taking Toprol-xl.
Among them, 38 people (0.1%) have Thrombophlebitis.

Among these 38 people:
How long have people been on Toprol-xl when they have Thrombophlebitis? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 100 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Thrombophlebitis when taking Toprol-xl? *
- female: 76.32 %
- male: 23.68 %
What is the age of people who have Thrombophlebitis when taking Toprol-xl? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 34.29 %
- 40-49: 17.14 %
- 50-59: 11.43 %
- 60+: 37.14 %
What are other drugs people take besides Toprol-xl? *
- Aspirin: 10 people, 26.32%
- Lasix: 10 people, 26.32%
- Xanax: 8 people, 21.05%
- Lisinopril: 8 people, 21.05%
- Nexium: 8 people, 21.05%
- Vioxx: 8 people, 21.05%
- Imdur: 7 people, 18.42%
- Restoril: 7 people, 18.42%
- Lipitor: 7 people, 18.42%
- Lortab: 7 people, 18.42%
What are other side effects people have besides Thrombophlebitis? *
- Chest Pain: 11 people, 28.95%
- Headache (pain in head): 10 people, 26.32%
- Weight Decreased: 9 people, 23.68%
- Stress And Anxiety: 9 people, 23.68%
- High Blood Cholesterol: 9 people, 23.68%
- Nausea (feeling of having an urge to vomit): 9 people, 23.68%
- Hypoaesthesia (reduced sense of touch or sensation): 9 people, 23.68%
- Cardiac Failure Congestive: 8 people, 21.05%
- Cardiac Disorder: 8 people, 21.05%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 8 people, 21.05%
What are the existing conditions these people have? *
- Birth Control: 8 people, 21.05%
- Joint Pain: 5 people, 13.16%
- Pain: 3 people, 7.89%
- Acne (skin problems that cause pimples): 2 people, 5.26%
- Ovarian Cancer (cancer of ovary): 2 people, 5.26%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 5.26%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 5.26%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 5.26%
- Premenstrual Syndrome: 2 people, 5.26%
- Asthma: 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Toprol-xl and have Thrombophlebitis?
- Check whether Thrombophlebitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Toprol-xl:
- Toprol-xl (40,636 reports)
Thrombophlebitis treatments and more:
- Thrombophlebitis (13,501 reports)
How severe was Thrombophlebitis and when was it recovered:
Expand to all the drugs that have ingredients of metoprolol succinate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Toprol-xl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Thrombophlebitis:
- Thrombophlebitis (941 drugs)
Browse all the conditions that are associated with Thrombophlebitis:
- Thrombophlebitis (1,267 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Toprol-xl) and Toprol-xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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