Tradjenta and Hot flushes aggravated - a phase IV clinical study of FDA data

Summary:

Hot flushes aggravated is reported as a side effect among people who take Tradjenta (linagliptin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Prostate cancer.

The phase IV clinical study analyzes which people have Hot flushes aggravated when taking Tradjenta. It is created by eHealthMe based on reports of 9,889 people who have side effects when taking Tradjenta from the FDA, and is updated regularly.

What is Tradjenta?

Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.

What is Hot flushes aggravated?

Hot flushes aggravated (sudden feelings of heat) is found to be associated with 1,521 drugs and 475 conditions by eHealthMe. Check the latest studies of Hot flushes aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

9,889 people reported to have side effects when taking Tradjenta.
Among them, 25 people (0.25%) have Hot flushes aggravated.

Could Tradjenta cause Hot flushes aggravated?

Among these 25 people:

How long have people been on Tradjenta when they have Hot flushes aggravated? *

What is the gender of people who have Hot flushes aggravated when taking Tradjenta? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Hot flushes aggravated when taking Tradjenta? *

What are other drugs people take besides Tradjenta? *

What are other side effects people have besides Hot flushes aggravated? *

Fatigue (feeling of tiredness): 12 people, 48.00%
Weight Increased: 7 people, 28.00%
Rashes (redness): 7 people, 28.00%
Diarrhea: 7 people, 28.00%
Joint Pain: 6 people, 24.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 20.00%
Drowsiness: 5 people, 20.00%
Dizziness: 5 people, 20.00%
Peripheral Swelling: 5 people, 20.00%
Itching: 4 people, 16.00%

What are the existing conditions these people have? *

Prostate Cancer: 4 people, 16.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 8.00%
Cough: 2 people, 8.00%
Stress And Anxiety: 1 person, 4.00%
Prostate Cancer Metastatic: 1 person, 4.00%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 4.00%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 4.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 4.00%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tradjenta and have Hot flushes aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tradjenta:

Tradjenta (9,987 reports)

Browse all side effects of Tradjenta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flushes aggravated:

Hot flushes aggravated (1,521 drugs)

Browse all the conditions that are associated with Hot flushes aggravated:

Hot flushes aggravated (475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on linagliptin (the active ingredients of Tradjenta) and Tradjenta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.