Tradjenta and Liver disorder - a phase IV clinical study of FDA data
Summary:
Liver disorder is reported as a side effect among people who take Tradjenta (linagliptin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ozempic, and have Cardiac disorder.
The phase IV clinical study analyzes which people have Liver disorder when taking Tradjenta. It is created by eHealthMe based on reports of 9,889 people who have side effects when taking Tradjenta from the FDA, and is updated regularly.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
What is Liver disorder?
Liver disorder (liver diseases) is found to be associated with 1,732 drugs and 2,047 conditions by eHealthMe. Check the latest studies of Liver disorder.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
9,889 people reported to have side effects when taking Tradjenta.
Among them, 14 people (0.14%) have Liver disorder.

Among these 14 people:
How long have people been on Tradjenta when they have Liver disorder? *
- < 1 month: 50 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 25 %
- 2 - 5 years: 25 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Liver disorder when taking Tradjenta? *
- female: 50 %
- male: 50 %
What is the age of people who have Liver disorder when taking Tradjenta? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 18.18 %
- 40-49: 0.0 %
- 50-59: 18.18 %
- 60+: 63.64 %
What are other drugs people take besides Tradjenta? *
- Lantus: 2 people, 14.29%
- Ozempic: 2 people, 14.29%
- Zytiga: 1 person, 7.14%
- Metformin: 1 person, 7.14%
- Eligard: 1 person, 7.14%
- Glimepiride: 1 person, 7.14%
- Insulin: 1 person, 7.14%
- Januvia: 1 person, 7.14%
- Lantus Solostar: 1 person, 7.14%
- Montelukast Sodium: 1 person, 7.14%
What are other side effects people have besides Liver disorder? *
- Urinary Tract Infection: 2 people, 14.29%
- Belching (release of gas from the digestive tract): 2 people, 14.29%
- Blood Glucose Increased: 2 people, 14.29%
- Ocular Hyperaemia (an abnormally large amount of blood in eye): 2 people, 14.29%
- Constipation: 2 people, 14.29%
- Diarrhea: 2 people, 14.29%
- Eye Pain: 2 people, 14.29%
- Gallstones (stone formation by bile component): 1 person, 7.14%
- Blood Pressure Abnormal: 1 person, 7.14%
- Cardiac Disorder: 1 person, 7.14%
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
- Prostate Cancer: 1 person, 7.14%
- Neoplasm Malignant (cancer tumour): 1 person, 7.14%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%
- Hyperglycemia (high blood sugar): 1 person, 7.14%
- High Blood Cholesterol: 1 person, 7.14%
- Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 7.14%
- Cubital Tunnel Syndrome (a condition brought on by increased pressure on the ulnar nerve at the elbow): 1 person, 7.14%
- Constipation: 1 person, 7.14%
- Cardiac Disorder: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Tradjenta and have Liver disorder?
- Check whether Liver disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tradjenta:
- Tradjenta (9,987 reports)
Liver disorder treatments and more:
- Liver disorder (57,384 reports)
How severe was Liver disorder and when was it recovered:
Expand to all the drugs that have ingredients of linagliptin:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Liver disorder:
- Liver disorder (1,732 drugs)
Browse all the conditions that are associated with Liver disorder:
- Liver disorder (2,047 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on linagliptin (the active ingredients of Tradjenta) and Tradjenta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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