Tramadol and Penis disorder - a phase IV clinical study of FDA data

Summary:

Penis disorder is reported as a side effect among people who take Tramadol (tramadol hydrochloride), especially for people who are 60+ old, have been taking the drug for 1 - 6 months also take Paracetamol, and have Sciatica.

The phase IV clinical study analyzes which people have Penis disorder when taking Tramadol. It is created by eHealthMe based on reports of 229,782 people who have side effects when taking Tramadol from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,798 Tramadol users. Check the latest studies of Tramadol.

What is Penis disorder?

Penis disorder is found to be associated with 196 drugs and 405 conditions by eHealthMe. Check the latest studies of Penis disorder.



On Jul, 16, 2026

229,782 people reported to have side effects when taking Tramadol.
Among them, 13 people (0.01%) have Penis disorder.

Could Tramadol cause Penis disorder?

Among these 13 people:

How long have people been on Tramadol when they have Penis disorder? *

  • < 1 month: 16.67 %
  • 1 - 6 months: 83.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Penis disorder when taking Tramadol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 40 %
  • 60+: 50 %

What are other drugs people take besides Tramadol? *

  1. Paracetamol: 5 people, 38.46%
  2. Humira: 2 people, 15.38%
  3. Xiaflex: 1 person, 7.69%
  4. Methotrexate: 1 person, 7.69%
  5. Magnesium Oxide: 1 person, 7.69%
  6. Lovenox: 1 person, 7.69%
  7. Lisinopril And Hydrochlorothiazide: 1 person, 7.69%
  8. Lamictal: 1 person, 7.69%
  9. Hydrocodone: 1 person, 7.69%
  10. Gabapentin: 1 person, 7.69%

What are other side effects people have besides Penis disorder? *

  1. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 6 people, 46.15%
  2. Nausea (feeling of having an urge to vomit): 5 people, 38.46%
  3. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 38.46%
  4. Constipation: 5 people, 38.46%
  5. Vision Blurred: 5 people, 38.46%
  6. Micturition Urgency (urgency to pass the urine): 5 people, 38.46%
  7. Mood Swings (an extreme or rapid change in mood): 5 people, 38.46%
  8. Abnormal Loss Of Weight: 5 people, 38.46%
  9. Negative Thoughts: 5 people, 38.46%
  10. Urination - Painful: 5 people, 38.46%

What are the existing conditions these people have? *

  1. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 5 people, 38.46%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 15.38%
  3. Muscle Spasms (muscle contraction): 1 person, 7.69%
  4. Hidradenitis (chronic disease of a type of sweat gland): 1 person, 7.69%
  5. Curvature Of The Penis: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tramadol and have Penis disorder?

- Check whether Penis disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tramadol:

Penis disorder treatments and more:

How severe was Penis disorder and when was it recovered:

Expand to all the drugs that have ingredients of tramadol hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tramadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Penis disorder:

Browse all the conditions that are associated with Penis disorder:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Tramadol) and Tramadol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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