Tramadol and Rheumatoid factor positive - a phase IV clinical study of FDA data

Summary:

Rheumatoid factor positive is reported as a side effect among people who take Tramadol (tramadol hydrochloride), especially for people who are female, 40-49 old, also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Rheumatoid factor positive when taking Tramadol. It is created by eHealthMe based on reports of 229,782 people who have side effects when taking Tramadol from the FDA, and is updated regularly.

What is Tramadol?

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,800 Tramadol users. Check the latest studies of Tramadol.

What is Rheumatoid factor positive?

Rheumatoid factor positive is found to be associated with 300 drugs and 195 conditions by eHealthMe. Check the latest studies of Rheumatoid factor positive.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

229,782 people reported to have side effects when taking Tramadol.
Among them, 237 people (0.1%) have Rheumatoid factor positive.

Could Tramadol cause Rheumatoid factor positive?

Among these 237 people:

What is the gender of people who have Rheumatoid factor positive when taking Tramadol? *

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What is the age of people who have Rheumatoid factor positive when taking Tramadol? *

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* Approximation only. Some reports may have incomplete information.

Do you take Tramadol and have Rheumatoid factor positive?

- Check whether Rheumatoid factor positive is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tramadol:

Tramadol (235,800 reports)

Rheumatoid factor positive treatments and more:

Rheumatoid factor positive (7,255 reports)

How severe was Rheumatoid factor positive and when was it recovered:

Rheumatoid factor positive in Tramadol

Expand to all the drugs that have ingredients of tramadol hydrochloride:

Rheumatoid factor positive and drugs with ingredients of tramadol hydrochloride (253 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tramadol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rheumatoid factor positive:

Rheumatoid factor positive (300 drugs)

Browse all the conditions that are associated with Rheumatoid factor positive:

Rheumatoid factor positive (195 conditions)

Related publications that referenced our studies

Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Tramadol) and Tramadol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.