Travatan and Punctate keratitis - a phase IV clinical study of FDA data

Summary:

Punctate keratitis is reported as a side effect among people who take Travatan (travoprost), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Simbrinza, and have Dry eyes.

The phase IV clinical study analyzes which people have Punctate keratitis when taking Travatan. It is created by eHealthMe based on reports of 12,807 people who have side effects when taking Travatan from the FDA, and is updated regularly.

What is Travatan?

Travatan has active ingredients of travoprost. It is often used in glaucoma. eHealthMe is studying from 13,103 Travatan users. Check the latest studies of Travatan.

What is Punctate keratitis?

Punctate keratitis (inflammation of the cornea with tiny spots) is found to be associated with 91 drugs and 225 conditions by eHealthMe. Check the latest studies of Punctate keratitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

12,807 people reported to have side effects when taking Travatan.
Among them, 12 people (0.09%) have Punctate keratitis.

Could Travatan cause Punctate keratitis?

Among these 12 people:

How long have people been on Travatan when they have Punctate keratitis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 25 %
  • 10+ years: 0.0 %

What is the gender of people who have Punctate keratitis when taking Travatan? *

  • female: 63.64 %
  • male: 36.36 %

What is the age of people who have Punctate keratitis when taking Travatan? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 12.5 %
  • 60+: 87.5 %

What are other drugs people take besides Travatan? *

  1. Azopt: 3 people, 25.00%
  2. Simbrinza: 3 people, 25.00%
  3. Brimonidine: 2 people, 16.67%
  4. Xiidra: 1 person, 8.33%
  5. Cosopt: 1 person, 8.33%
  6. Betoptic S: 1 person, 8.33%
  7. Brinzolamide: 1 person, 8.33%
  8. Coenzyme Q10: 1 person, 8.33%
  9. Coreg: 1 person, 8.33%
  10. Coumadin: 1 person, 8.33%

What are other side effects people have besides Punctate keratitis? *

  1. Eye Pruritus (eye itching): 4 people, 33.33%
  2. Ocular Hyperaemia (an abnormally large amount of blood in eye): 4 people, 33.33%
  3. Eye Pain: 3 people, 25.00%
  4. Photophobia (extreme sensitivity to light): 3 people, 25.00%
  5. Eye Irritation: 3 people, 25.00%
  6. Foreign Body Sensation In Eyes (feeling of something in eye): 3 people, 25.00%
  7. Conjunctivitis (pink eye): 3 people, 25.00%
  8. Intraocular Pressure Increased: 3 people, 25.00%
  9. Visual Acuity Reduced (reduced clearness of vision): 3 people, 25.00%
  10. Rashes (redness): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 1 person, 8.33%
  2. Normal Tension Glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye): 1 person, 8.33%
  3. Migraine (headache): 1 person, 8.33%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%
  5. Hiv Infection: 1 person, 8.33%
  6. Dry Eyes (lack of adequate tears): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Travatan and have Punctate keratitis?

- Check whether Punctate keratitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Travatan:

Punctate keratitis treatments and more:

How severe was Punctate keratitis and when was it recovered:

Expand to all the drugs that have ingredients of travoprost:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Travatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Punctate keratitis:

Browse all the conditions that are associated with Punctate keratitis:


How the study uses the data?

The study uses data from the FDA. It is based on travoprost (the active ingredients of Travatan) and Travatan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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