Treanda and Hyponatraemia aggravated - a phase IV clinical study of FDA data

Summary:

Hyponatraemia aggravated is reported as a side effect among people who take Treanda (bendamustine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Rituxan, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Hyponatraemia aggravated when taking Treanda. It is created by eHealthMe based on reports of 4,378 people who have side effects when taking Treanda from the FDA, and is updated regularly.

What is Treanda?

Treanda has active ingredients of bendamustine hydrochloride. It is often used in non-hodgkin's lymphoma. eHealthMe is studying from 4,411 Treanda users. Check the latest studies of Treanda.

What is Hyponatraemia aggravated?

Hyponatraemia aggravated (abnormally low concentrations of sodium ions in the circulating blood) is found to be associated with 1,505 drugs and 543 conditions by eHealthMe. Check the latest studies of Hyponatraemia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

4,378 people reported to have side effects when taking Treanda.
Among them, 17 people (0.39%) have Hyponatraemia aggravated.

Could Treanda cause Hyponatraemia aggravated?

Among these 17 people:

How long have people been on Treanda when they have Hyponatraemia aggravated? *

What is the gender of people who have Hyponatraemia aggravated when taking Treanda? *

female: 37.5 %
male: 62.5 %

What is the age of people who have Hyponatraemia aggravated when taking Treanda? *

What are other drugs people take besides Treanda? *

What are other side effects people have besides Hyponatraemia aggravated? *

Confusional State: 5 people, 29.41%
Constipation: 4 people, 23.53%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 17.65%
Back Pain: 3 people, 17.65%
Dizziness: 3 people, 17.65%
Hypokalemia (low potassium): 3 people, 17.65%
Demyelinating Polyneuropathy (disorder that affects the nerves outside of the brain and spinal cord (peripheral nerves)): 3 people, 17.65%
Gait Disturbance: 3 people, 17.65%
Cardiac Failure Congestive: 3 people, 17.65%
Pneumonia: 3 people, 17.65%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 29.41%
Lymphoma (cancer that begins in immune system cells): 3 people, 17.65%
Burkitt Lymphoma (cancer of the lymphatic system): 2 people, 11.76%
Enlarged Prostate: 2 people, 11.76%
Rashes (redness): 2 people, 11.76%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 11.76%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 11.76%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 11.76%
Neuropathy Peripheral (surface nerve damage): 2 people, 11.76%
Nausea (feeling of having an urge to vomit): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Treanda and have Hyponatraemia aggravated?

- Check whether Hyponatraemia aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Treanda:

Treanda (4,411 reports)

Browse all side effects of Treanda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatraemia aggravated:

Hyponatraemia aggravated (1,506 drugs)

Browse all the conditions that are associated with Hyponatraemia aggravated:

Hyponatraemia aggravated (543 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bendamustine hydrochloride (the active ingredients of Treanda) and Treanda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.