Trelegy ellipta and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Trelegy ellipta (fluticasone furoate; umeclidinium bromide; vilanterol trifenatate), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Vitamin D3, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Trelegy ellipta. It is created by eHealthMe based on reports of 27,966 people who have side effects when taking Trelegy ellipta from the FDA, and is updated regularly.

What is Trelegy ellipta?

Trelegy ellipta has active ingredients of fluticasone furoate; umeclidinium bromide; vilanterol trifenatate. eHealthMe is studying from 28,101 Trelegy ellipta users. Check the latest studies of Trelegy ellipta.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,957 drugs and 2,937 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On Jul, 17, 2026

27,966 people reported to have side effects when taking Trelegy ellipta.
Among them, 32 people (0.11%) have Hyperkalemia.

Could Trelegy ellipta cause Hyperkalemia?

Among these 32 people:

How long have people been on Trelegy ellipta when they have Hyperkalemia? *

What is the gender of people who have Hyperkalemia when taking Trelegy ellipta? *

female: 40 %
male: 60 %

What is the age of people who have Hyperkalemia when taking Trelegy ellipta? *

What are other drugs people take besides Trelegy ellipta? *

Acetaminophen: 7 people, 21.88%
Vitamin D3: 7 people, 21.88%
Albuterol Sulfate: 6 people, 18.75%
Aspirin: 5 people, 15.62%
Sodium Chloride: 5 people, 15.62%
Epinephrine: 4 people, 12.50%
Bactrim: 4 people, 12.50%
Omeprazole: 4 people, 12.50%
Diphenhydramine Hydrochloride: 4 people, 12.50%
Proair Hfa: 4 people, 12.50%

What are other side effects people have besides Hyperkalemia? *

Bradycardia (abnormally slow heart action): 12 people, 37.50%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 10 people, 31.25%
Urinary Tract Infection: 7 people, 21.88%
Fall: 5 people, 15.62%
Fatigue (feeling of tiredness): 4 people, 12.50%
Pneumonia: 4 people, 12.50%
Concussion (short loss of normal brain function in response to a head injury): 3 people, 9.38%
Drug Hypersensitivity: 3 people, 9.38%
Cerebral Haemorrhage (bleeding within the brain): 3 people, 9.38%
Blood Potassium Abnormal: 3 people, 9.38%

What are the existing conditions these people have? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 13 people, 40.62%
Type 2 Diabetes: 10 people, 31.25%
Oesophagitis (inflammation of oesophagus): 10 people, 31.25%
High Blood Pressure: 10 people, 31.25%
Immunodeficiency Common Variable: 6 people, 18.75%
Muscle Spasms (muscle contraction): 2 people, 6.25%
Pain: 2 people, 6.25%
Bacterial Infection: 1 person, 3.12%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.12%
Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Trelegy ellipta and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trelegy ellipta:

Trelegy ellipta (28,101 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

How severe was Hyperkalemia and when was it recovered:

Hyperkalemia in Trelegy ellipta

Expand to all the drugs that have ingredients of fluticasone furoate; umeclidinium bromide; vilanterol trifenatate:

Hyperkalemia and drugs with ingredients of fluticasone furoate; umeclidinium bromide; vilanterol trifenatate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trelegy ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,957 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,937 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone furoate; umeclidinium bromide; vilanterol trifenatate (the active ingredients of Trelegy ellipta) and Trelegy ellipta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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