Tremfya and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Tremfya (guselkumab), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Lyrica, and have Psoriasis.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Tremfya. It is created by eHealthMe based on reports of 22,544 people who have side effects when taking Tremfya from the FDA, and is updated regularly.

What is Tremfya?

Tremfya has active ingredients of guselkumab. eHealthMe is studying from 22,557 Tremfya users. Check the latest studies of Tremfya.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,084 drugs and 1,365 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

22,544 people reported to have side effects when taking Tremfya.
Among them, 22 people (0.1%) have Multiple sclerosis.

Among these 22 people:

How long have people been on Tremfya when they have Multiple sclerosis? *

What is the gender of people who have Multiple sclerosis when taking Tremfya? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Multiple sclerosis when taking Tremfya? *

What are other drugs people take besides Tremfya? *

Vitamin D: 3 people, 13.64%
Vitamin B12: 3 people, 13.64%
Lyrica: 3 people, 13.64%
Stelara: 2 people, 9.09%
Humira: 1 person, 4.55%

What are other side effects people have besides Multiple sclerosis? *

Vitamin B12 Deficiency: 3 people, 13.64%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 13.64%
Back Pain: 3 people, 13.64%
Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 2 people, 9.09%
Headache (pain in head): 2 people, 9.09%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 4.55%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 4.55%
Otitis (ear infection): 1 person, 4.55%
Injection Site Reaction: 1 person, 4.55%
Drug Ineffective: 1 person, 4.55%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 14 people, 63.64%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tremfya and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tremfya:

Tremfya (22,557 reports)

Browse all side effects of Tremfya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Multiple sclerosis (1,084 drugs)

Browse all the conditions that are associated with Multiple sclerosis:

Multiple sclerosis (1,365 conditions)

Related publications that referenced our studies

Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on guselkumab (the active ingredients of Tremfya) and Tremfya (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.