Tremfya and Seizures - a phase IV clinical study of FDA data

Summary:

Seizures is reported as a side effect among people who take Tremfya (guselkumab), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Clonidine, and have Psoriasis.

The phase IV clinical study analyzes which people have Seizures when taking Tremfya. It is created by eHealthMe based on reports of 22,544 people who have side effects when taking Tremfya from the FDA, and is updated regularly.

What is Tremfya?

Tremfya has active ingredients of guselkumab. eHealthMe is studying from 22,557 Tremfya users. Check the latest studies of Tremfya.

What is Seizures?

Seizures (abnormal excessive or synchronous neuronal activity in the brain) is found to be associated with 1,990 drugs and 2,282 conditions by eHealthMe. Check the latest studies of Seizures.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

22,544 people reported to have side effects when taking Tremfya.
Among them, 33 people (0.15%) have Seizures.

Among these 33 people:

How long have people been on Tremfya when they have Seizures? *

What is the gender of people who have Seizures when taking Tremfya? *

female: 35.48 %
male: 64.52 %

What is the age of people who have Seizures when taking Tremfya? *

What are other drugs people take besides Tremfya? *

What are other side effects people have besides Seizures? *

Post Procedural Complication: 3 people, 9.09%
Cardiac Arrest: 3 people, 9.09%
Confusional State: 3 people, 9.09%
Fever: 3 people, 9.09%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 9.09%
Pneumonia: 3 people, 9.09%
Memory Loss: 3 people, 9.09%
The Flu (the flu is caused by an influenza virus): 2 people, 6.06%
Synovitis (inflammation of the synovial membrane): 2 people, 6.06%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 6.06%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 17 people, 51.52%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 21.21%
Nerve Injury: 3 people, 9.09%
High Blood Pressure: 3 people, 9.09%
High Blood Cholesterol: 3 people, 9.09%
Necrotising Fasciitis (an uncommon life-threatening soft-tissue infection): 1 person, 3.03%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Tremfya and have Seizures?

- Check whether Seizures is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tremfya:

Tremfya (22,557 reports)

Seizures treatments and more:

Seizures (150,180 reports)

Browse all side effects of Tremfya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Seizures:

Seizures (1,990 drugs)

Browse all the conditions that are associated with Seizures:

Seizures (2,282 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guselkumab (the active ingredients of Tremfya) and Tremfya (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.