Tretinoin and Fluid overload - a phase IV clinical study of FDA data

Summary:

Fluid overload is reported as a side effect among people who take Tretinoin (tretinoin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ferrous Fumarate, and have Upper respiratory tract infection.

The phase IV clinical study analyzes which people have Fluid overload when taking Tretinoin. It is created by eHealthMe based on reports of 6,353 people who have side effects when taking Tretinoin from the FDA, and is updated regularly.

What is Tretinoin?

Tretinoin has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 6,479 Tretinoin users. Check the latest studies of Tretinoin.

What is Fluid overload?

Fluid overload (too much fluid in the blood) is found to be associated with 1,023 drugs and 1,051 conditions by eHealthMe. Check the latest studies of Fluid overload.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

6,353 people reported to have side effects when taking Tretinoin.
Among them, 15 people (0.24%) have Fluid overload.

Among these 15 people:

How long have people been on Tretinoin when they have Fluid overload? *

What is the gender of people who have Fluid overload when taking Tretinoin? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Fluid overload when taking Tretinoin? *

What are other drugs people take besides Tretinoin? *

What are other side effects people have besides Fluid overload? *

Cardiac Failure Congestive: 11 people, 73.33%
Oedema Peripheral (superficial swelling): 11 people, 73.33%
Pneumonia: 11 people, 73.33%
Diarrhea: 10 people, 66.67%
Mitral Valve Incompetence (inefficient heart valve): 10 people, 66.67%
Hypovolaemia (a decreased volume of circulating blood in the body): 10 people, 66.67%
Pericardial Effusion (fluid around the heart): 10 people, 66.67%
Fatigue (feeling of tiredness): 10 people, 66.67%
Renal Injury (kidney injury): 10 people, 66.67%
Right Ventricular Systolic Pressure Increased: 10 people, 66.67%

What are the existing conditions these people have? *

Upper Respiratory Tract Infection: 10 people, 66.67%
Acute Promyelocytic Leukaemia (cancer of the blood and bone marrow): 8 people, 53.33%
Latent Tuberculosis (hidden tuberculosis): 7 people, 46.67%
High Blood Pressure: 2 people, 13.33%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 6.67%
Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%
Pain: 1 person, 6.67%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Muscle Spasms (muscle contraction): 1 person, 6.67%
Joint Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Tretinoin and have Fluid overload?

- Check whether Fluid overload is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tretinoin:

Tretinoin (6,479 reports)

Fluid overload treatments and more:

Fluid overload (20,385 reports)

Browse all side effects of Tretinoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid overload:

Fluid overload (1,023 drugs)

Browse all the conditions that are associated with Fluid overload:

Fluid overload (1,051 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tretinoin (the active ingredients of Tretinoin) and Tretinoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.