Tri-luma and Overdose - a phase IV clinical study of FDA data

Summary:

Overdose is reported as a side effect among people who take Tri-luma (fluocinolone acetonide; hydroquinone; tretinoin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Klonopin, and have Melasma.

The phase IV clinical study analyzes which people have Overdose when taking Tri-luma. It is created by eHealthMe based on reports of 588 people who have side effects when taking Tri-luma from the FDA, and is updated regularly.

What is Tri-luma?

Tri-luma has active ingredients of fluocinolone acetonide; hydroquinone; tretinoin. eHealthMe is studying from 591 Tri-luma users. Check the latest studies of Tri-luma.

What is Overdose?

Overdose is found to be associated with 2,213 drugs and 2,474 conditions by eHealthMe. Check the latest studies of Overdose.

On Jul, 29, 2026

588 people reported to have side effects when taking Tri-luma.
Among them, 11 people (1.87%) have Overdose.

Among these 11 people:

How long have people been on Tri-luma when they have Overdose? *

What is the gender of people who have Overdose when taking Tri-luma? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Overdose when taking Tri-luma? *

What are other drugs people take besides Tri-luma? *

What are other side effects people have besides Overdose? *

Drug Ineffective: 3 people, 27.27%
Skin Burning Sensation: 3 people, 27.27%
Rashes (redness): 3 people, 27.27%
Sleep Disorder: 2 people, 18.18%
Skin Hyperpigmentation (disorders affect the colour of your skin): 2 people, 18.18%
Depression: 2 people, 18.18%
Dry Skin: 2 people, 18.18%
Back Disorder: 2 people, 18.18%
Rash Macular (small, flat red spots): 1 person, 9.09%
Feeling Hot: 1 person, 9.09%

What are the existing conditions these people have? *

Melasma (the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration): 3 people, 27.27%
Skin Discoloration: 2 people, 18.18%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 18.18%
Skin Hyperpigmentation (disorders affect the colour of your skin): 1 person, 9.09%
Pigmentation Disorder (disturbances of human skin colour): 1 person, 9.09%
Lichen Planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash): 1 person, 9.09%
Diabetes: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tri-luma and have Overdose?

- Check whether Overdose is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tri-luma:

Tri-luma (591 reports)

Overdose treatments and more:

Overdose (229,245 reports)

How severe was Overdose and when was it recovered:

Overdose in Tri-luma

Expand to all the drugs that have ingredients of fluocinolone acetonide; hydroquinone; tretinoin:

Overdose and drugs with ingredients of fluocinolone acetonide; hydroquinone; tretinoin

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tri-luma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Overdose:

Overdose (2,214 drugs)

Browse all the conditions that are associated with Overdose:

Overdose (2,474 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluocinolone acetonide; hydroquinone; tretinoin (the active ingredients of Tri-luma) and Tri-luma (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.